Research advances on multifunctional hydrogel dressings for treatment of diabetic chronic wounds

WB Cao, CY Gao - Zhonghua Shao Shang za zhi= Zhonghua …, 2021 - europepmc.org
Diabetes can lead to a variety of complications, such as chronic wound (diabetic foot), which
is one of the important causes of death for patients with diabetes. Unfavorable factors such …

[HTML][HTML] 多功能水凝胶敷料治疗糖尿病致慢性创面的研究进展

曹望北, 高长有 - 中华烧伤与创面修复杂志, 2021 - zhsszz.xml-journal.net
糖尿病会导致多种并发症如慢性创面(糖尿病足), 是导致糖尿病患者死亡的重要原因之一.
高血糖, 高氧化应激水平, 高炎症水平以及易感染等不利因素使糖尿病致慢性创面难以愈合 …

Mineralized polyplexes for gene delivery: Improvement of transfection efficiency as a consequence of calcium incubation and not mineralization

TA Dick, H Uludağ - Materials Science and Engineering: C, 2021 - Elsevier
Gene therapy is an emerging field in which nucleic acids are used to control protein
expression. The necessity of delivering nucleic acids to specific cell types and intracellular …

Nanotechnology to the rescue: treatment perspective for the immune dysregulation observed in COVID-19

AE Peter, BV Sandeep, BG Rao… - Frontiers in …, 2021 - frontiersin.org
The study of the use of nanotechnology for drug delivery has been extensive. Nanomedical
approaches for therapeutics; drug delivery in particular is superior to conventional methods …

Channels to consciousness: a possible role of gap junctions in consciousness

D Dere, A Zlomuzica, E Dere - Reviews in the Neurosciences, 2021 - degruyter.com
The neurophysiological basis of consciousness is still unknown and one of the most
challenging questions in the field of neuroscience and related disciplines. We propose that …

Relating Mobility of dsRNA in Nanoporous Silica Particles to Loading and Release Behavior

S Zhou, EA Nadeau, MA Khan, BA Webb… - ACS Applied Bio …, 2021 - ACS Publications
Nanoparticle delivery of polynucleic acids traditionally relies on the modulation of surface
interactions to achieve loading and release. This work investigates the additional role of …

Avoiding High‐Pressure Problem for Modified RNA‐attached Polystyrene Support by Pre‐Swelling Using Toluene in the Oligonucleotide Synthesis

SW Kim, YI Cho, KE Jung - Bulletin of the Korean Chemical …, 2021 - Wiley Online Library
This study describes a method to avoid the high‐pressure problem caused by swelling
during the detritylation step in oligonucleotide solid‐phase synthesis using a modified RNA …

An overview of nano delivery systems for targeting RNA interference-based therapy in ulcerative colitis

IM Alfagih, BN Aldosari, BT AlQuadeib… - Current …, 2021 - ingentaconnect.com
Ulcerative colitis (UC) is one of the main subtypes of inflammatory bowel disease. UC has a
negative effect on patients' quality of life, and it is an important risk factor for the development …

Mesoporous silica nanoparticles for combined delivery of polo-like kinase 1 (PLK1) and epidermal growth factor receptor (EGFR) inhibitors enhances radio sensibility …

C Li, Z Chen, X Li, H Xiao, Q Liu, L Zhao… - Science of Advanced …, 2021 - ingentaconnect.com
The aim of this study was to clarify the role of nanoparticle for combined delivery of polo-like
kinase 1 (PLK1) and EGFR inhibitors in non-small cell lung cancer progress in vitro and its …

Regulatory role of micro-RNAs in plants under challenging environmental conditions with special focus on drought and salinity

A Kumar, R Kaur, MV Rajam - Harsh Environment and Plant Resilience …, 2021 - Springer
Micro-RNAs (miRNAs) are small, 20–24 nucleotide long, non-coding RNAs that can
coordinate vital regulatory functions in key metabolic processes in plants. Their primary …