Aims Focal segmental glomerulosclerosis (FSGS) is the common cause of chronic renal
disease worldwide. Although there are many etiologic factors which have common theme of …

Autophagy plays a key role in the pathogenesis of kidney diseases, however its role in
diabetic nephropathy (DN), and particularly in kidney glomerular mesangial cells (MCs) is …

MicroRNAs are involved in the regulation of the autophagy and proliferation in several
diseases. This study aims to verify the role of miR-25-3p in the proliferation and autophagy …

Background: Focal segmental glomerulosclerosis (FSGS) is a frequent and severe
glomerular disease characterized by destabilization of podocyte foot processes. Emerging …

Background/Aims: Renal interstitial fibrosis (RIF) is a common feature that facilitates the
progression of chronic kidney disease (CKD), and emerging lines of evidence suggest that …

Renal ischemia/reperfusion (I/R) injury often occurs during multiple organ failure and sepsis,
and autophagy may serve a role in I/R injury. The aim of the present study was to explore the …

MicroRNAs plays important roles in the progression of diabetic nephropathy (DN) and
podocyte injury. This study aimed to investigate the role and regulation mechanism of miR …

Background: Acute kidney injury (AKI) is traditionally described as a condition leading to
rapid damage to kidney function, eventually becoming a significant healthcare concern with …

Introduction: Focal segmental glomerulosclerosis (FSGS) is characterized by focal and
segmental obliteration of glomerular capillary tufts with increased matrix and usually …

Focal segmental glomerulosclerosis (FSGS) is a common kidney disease that results in
nephrotic syndrome. FSGS arises from dysfunction and apoptosis of podocytes in the …