[HTML][HTML] MicroRNA expression profiling and biomarker validation in treatment-naïve and drug resistant non-small cell lung cancer

L MacDonagh, MF Gallagher, B Ffrench… - … lung cancer research, 2021 - ncbi.nlm.nih.gov
Background In the absence of targetable mutations or immune checkpoints, cisplatin-
doublet chemotherapy remains the standard of care in non-small cell lung cancer (NSCLC) …

Prognostic, therapeutic and diagnostic potential of microRNAs in non-small cell lung cancer

A Markou, Y Liang, E Lianidou - Clinical Chemistry and Laboratory …, 2011 - degruyter.com
Non-small cell lung carcinomas (NSCLC) account for about 80% of lung cancers and their
remarkable heterogeneity manifests in histology, pathogenesis, prognosis, and response to …

[HTML][HTML] Expression profiles of microRNAs in drug-resistant non-small cell lung cancer cell lines using microRNA sequencing

S Hu, Y Yuan, Z Song, D Yan, X Kong - Cellular Physiology and …, 2019 - karger.com
Background/Aims: Drug resistance remains a main obstacle to the treatment of non-small
cell lung cancer (NSCLC). The aim of this study was to identify the expression profiles of …

[HTML][HTML] MicroRNA profiling associated with non-small cell lung cancer: next generation sequencing detection, experimental validation, and prognostic value

S Gallach, E Jantus-Lewintre, S Calabuig-Fariñas… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Background The average five-year survival for non-small cell lung cancer (NSCLC) patients
is approximately 15%. Emerging evidence indicates that microRNAs (miRNAs) constitute a …

Prospects of microRNAs as therapeutic biomarkers in non-small cell lung cancer

JS Samson, VD Parvathi - Medical Oncology, 2023 - Springer
Lung Cancer, the second most common cancer worldwide, remains the leading cause of
cancer-related deaths, contemporarily. More than 85% of identified lung cancer cases are …

microRNAs as tumor inhibitors, oncogenes, biomarkers for drug efficacy and outcome predictors in lung cancer

YW Jiang, LA Chen - Molecular medicine reports, 2012 - spandidos-publications.com
Lung cancer remains the leading cause of cancer-related death worldwide for both men and
women, and non-small cell lung cancer (NSCLC) accounts for approximately 80% of all …

[HTML][HTML] Identification of microRNA differentially expressed in three subtypes of non-small cell lung cancer and in silico functional analysis

Y Hu, L Wang, J Gu, K Qu, Y Wang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Emerging studies demonstrated that miRNAs played fundamental roles in lung cancer. In
this study, we attempted to explore the clinical significance of the miRNA signature in …

[HTML][HTML] MicroRNAs as regulators of cisplatin-resistance in non-small cell lung carcinomas

I Fadejeva, H Olschewski, A Hrzenjak - Oncotarget, 2017 - ncbi.nlm.nih.gov
With more than 80% of all diagnosed lung cancer cases, non-small cell lung cancer
(NSCLC) remains the leading cause of cancer death worldwide. Exact diagnosis is mostly …

MicroRNA profiling in lung cancer reveals new molecular markers for diagnosis

CC Solomides, BJ Evans, JM Navenot, R Vadigepalli… - Acta cytologica, 2012 - karger.com
Objective: To identify new molecular diagnostic markers for non-small cell lung carcinoma
(NSCLC) by analyzing microRNA (miRNA) expression profile differences in samples from …

[HTML][HTML] Characterization of microRNA transcriptome in lung cancer by next-generation deep sequencing

J Ma, K Mannoor, L Gao, A Tan, MA Guarnera… - Molecular …, 2014 - Elsevier
Non-small cell lung cancer (NSCLC) is the leading cause of cancer death. Systematically
characterizing miRNAs in NSCLC will help develop biomarkers for its diagnosis and …