The correct balance between collagen synthesis and degradation is essential for almost
every aspect of life, from development to healthy aging, reproduction and wound healing …

PCPE-2 was discovered at the beginning of this century, and was soon identified as a close
homolog of PCPE-1 (procollagen C-proteinase enhancer 1). After the demonstration that it …

PCPE-1 (procollagen C-proteinase enhancer-1) is an extracellular matrix glycoprotein that
can stimulate procollagen processing by procollagen C-proteinases such as BMP-1 (bone …

Procollagen C-proteinase enhancer 1 (PCPE-1) is an extracellular matrix glycoprotein that
can stimulate procollagen processing by procollagen C-proteinases (PCPs) such as bone …

Tight regulation of collagen fibril deposition in the extracellular matrix is essential for normal
tissue homeostasis and repair, defects in which are associated with several degenerative or …

Current non-invasive diagnostic methods of fibrosis are limited in their ability to identify early
and intermediate stages of fibrosis and assess the efficacy of therapy. New biomarkers of …

Abstract BMP-1/tolloid-like proteinases (BTPs) are major players in tissue morphogenesis,
growth and repair. They act by promoting the deposition of structural extracellular matrix …

Procollagen C-proteinase enhancer-1 (PCPE-1) is an extracellular matrix (ECM)
glycoprotein that can stimulate procollagen processing by procollagen C-proteinases …

Members of the bone morphogenetic protein-1/tolloid (BMP-1/Tld) family of
metalloproteinases, also known as procollagen C-proteinases (PCPs), control multiple …

Excessive collagen deposition is a common complication of myocardial infarction that
causes progressive heart disease. Several pro-fibrotic cytokines and hormones, including …