[HTML][HTML] Epigenetic dysregulation in cardiovascular aging and disease

AB Herman, JR Occean, P Sen - The journal of cardiovascular …, 2021 - ncbi.nlm.nih.gov
Cardiovascular disease (CVD) is the leading cause of mortality and morbidity for all sexes,
racial and ethnic groups. Age, and its associated physiological and pathological …

Epigenetic modifications in cardiovascular aging and diseases

W Zhang, M Song, J Qu, GH Liu - Circulation research, 2018 - Am Heart Assoc
Aging is associated with a progressive decline in cardiovascular structure and function.
Accumulating evidence links cardiovascular aging to epigenetic alterations encompassing a …

Epigenetic age acceleration reflects long-term cardiovascular health

BT Joyce, T Gao, Y Zheng, J Ma, SJ Hwang… - Circulation …, 2021 - Am Heart Assoc
Rationale: Epigenetic aging is a novel measure of biological age, reflecting exposures and
disease risks independent of chronological age. It may serve as a useful biomarker of …

Epigenetics of aging and aging-related disease

A Brunet, SL Berger - Journals of Gerontology Series A …, 2014 - academic.oup.com
Aging is associated with a wide range of human disorders, including cancer, diabetes,
cardiovascular, and neurodegenerative diseases. Long thought to be an inexorable road …

New insights into the genetics and epigenetics of aging plasticity

J Zhang, S Wang, B Liu - Genes, 2023 - mdpi.com
Biological aging is characterized by irreversible cell cycle blockade, a decreased capacity
for tissue regeneration, and an increased risk of age-related diseases and mortality. A …

Targeting epigenetic mechanisms in vascular aging

Z Lin, Q Ding, X Li, Y Feng, H He, C Huang… - Frontiers in …, 2022 - frontiersin.org
Environment, diseases, lack of exercise, and aged tendency of population have becoming
crucial factors that induce vascular aging. Vascular aging is unmodifiable risk factor for …

Introduction to Cardiovascular Aging Compendium: “Aging as the Quintessential Complex Phenotype”

AJ Marian, A Bhatnagar, R Bolli… - Circulation …, 2018 - Am Heart Assoc
Recent advances in genomic technologies have enabled the identification of epigenetic
changes that occur in healthy aging and pathological conditions. The compendium includes …

Epigenetic mechanisms of longevity and aging

P Sen, PP Shah, R Nativio, SL Berger - Cell, 2016 - cell.com
Aging is an inevitable outcome of life, characterized by progressive decline in tissue and
organ function and increased risk of mortality. Accumulating evidence links aging to genetic …

Aging-associated changes in cardiac gene expression

M Volkova, R Garg, S Dick… - Cardiovascular research, 2005 - academic.oup.com
Cardiovascular diseases (eg, vascular diseases, strokes, heart failure) reach epidemic
proportions in the elderly and are the primary limits to survival in man. Age-associated …

[HTML][HTML] Advances in epigenetic regulation of vascular aging

J Jin, Y Liu, L Huang, H Tan - Reviews in Cardiovascular Medicine, 2019 - imrpress.com
Vascular aging is a major risk factor and driver of agerelated cardiovascular diseases
(CVD). Atherosclerosis, hypertension, and other CVD lead to vascular dysfunction that …