Antimicrobial stewardship is imperative when treating bacterial infections because the
misuse and overuse of antibiotics have caused pathogens to develop life-threatening …

The most common mechanism of the resistance to β-lactam antibiotics is the
expIdentification of cisplatin and palladiuression of β-lactamases, which can hydrolyze the β …

New Delhi metallo-β-lactamase-1 (NDM-1) can hydrolyze almost all antibiotics of the β-
lactam group, resulting in the generation of multidrug resistant bacteria. Besides its broad …

Objectives Human health is seriously threatened by metallo-β-lactamase (MBL)-mediated
bacterial antimicrobial resistance, among which New Delhi metallo-β-lactamase 1 (NDM-1) …

Multidrug bacterial resistance endangers clinically effective antimicrobial therapy and
continues to cause major public health problems, which have been upgraded to …

The worldwide emergence of New Delhi metallo-β-lactamase-1 (NDM-1) as a
carbapenemase able to hydrolyze nearly all available β-lactam antibiotics has characterized …

NDM-1 and its variants are the most prevalent types of metallo-β-lactamases, hydrolyze
almost all antibiotics of β-lactam group leading to multiple-drug resistance in bacteria. No …

Abstract Bacteria carrying New Delhi metallo-β-lactamase-1 (New Delhi metallo-β-
lactamase, NDM-1) resistance gene is a new type of “superbug”, which can hydrolyze …

A new member of the class metallo-β-lactamase (MBL), New Delhi metallo-beta-lactamase 1
(NDM-1) has emerged recently as a leading threat to the treatment of infections that have …

The emergence of NDM-1 containing multi-antibiotic resistant" Superbugs" necessitates the
needs of developing of novel NDM-1inhibitors. In this study, we report the discovery of novel …