Targeted overexpression of PPARγ in skeletal muscle by random insertion and CRISPR/Cas9 transgenic pig cloning enhances oxidative fiber formation and …

H Gu, Y Zhou, J Yang, J Li, Y Peng, X Zhang… - The FASEB …, 2021 - Wiley Online Library
Peroxisome proliferator‐activated receptor gamma (PPARγ) is a master regulator of
adipogenesis and lipogenesis. To understand its roles in fiber formation and fat deposition …

Study on quantitative expression of PPARγ and ADRP in muscle and its association with intramuscular fat deposition of pig

J Cui, W Chen, J Liu, T Xu, Y Zeng - SpringerPlus, 2016 - Springer
Background Intramuscular fat (intramuscular fat, IMF) is one of the important traits of pork
quality. How to reasonably improve the intramuscular fat content is the most focus …

PPARGC1A Is a Moderator of Skeletal Muscle Development Regulated by miR-193b-3p

M Ma, B Cai, S Kong, Z Zhou, J Zhang… - International Journal of …, 2022 - mdpi.com
Meat production performance is one of the most important factors in determining the
economic value of poultry. Myofiber is the basic unit of skeletal muscle, and its physical and …

Oxidative and glycolytic skeletal muscles show marked differences in gene expression profile in Chinese Qingyuan partridge chickens

S Jingting, X Qin, S Yanju, Z Ming, T Yunjie, J Gaige… - PLoS …, 2017 - journals.plos.org
Oxidative and glycolytic myofibers have different structures and metabolic characteristics
and their ratios are important in determining poultry meat quality. However, the molecular …

PGC1α expression is controlled in skeletal muscles by PPARβ, whose ablation results in fiber-type switching, obesity, and type 2 diabetes

M Schuler, F Ali, C Chambon, D Duteil, JM Bornert… - Cell metabolism, 2006 - cell.com
Mice in which peroxisome proliferator-activated receptor β (PPARβ) is selectively ablated in
skeletal muscle myocytes were generated to elucidate the role played by PPARβ signaling …

PPARγ controls ectopic adipogenesis and cross-talks with myogenesis during skeletal muscle regeneration

G Dammone, S Karaz, L Lukjanenko, C Winkler… - International journal of …, 2018 - mdpi.com
Skeletal muscle is a regenerative tissue which can repair damaged myofibers through the
activation of tissue-resident muscle stem cells (MuSCs). Many muscle diseases with …

Expression and cDNA cloning of porcine peroxisome proliferator-activated receptor gamma (PPARγ)

KL Houseknecht, CA Bidwell, CP Portocarrero… - Gene, 1998 - Elsevier
Peroxisome proliferator-activated receptor γ (PPARγ) is a member of the PPAR subfamily of
nuclear hormone receptors. In rodents and humans, expression of PPARγ is predominantly …

Docosahexaenoic acid regulates adipogenic genes in myoblasts via porcine peroxisome proliferator-activated receptor γ

YH Yu, EC Lin, SC Wu, WTK Cheng… - Journal of animal …, 2008 - academic.oup.com
The nuclear transcription factor peroxisome proliferator-activated receptor γ (PPARγ)
triggers adipocyte differentiation by regulating lipogenic genes. A ligand for PPARγ is …

[HTML][HTML] Skeletal muscle-specific overexpression of PGC-1α induces fiber-type conversion through enhanced mitochondrial respiration and fatty acid oxidation in mice …

L Zhang, Y Zhou, W Wu, L Hou, H Chen… - … journal of biological …, 2017 - ncbi.nlm.nih.gov
Individual skeletal muscles in the animal body are heterogeneous, as each is comprised of
different fiber types. Type I muscle fibers are rich with mitochondria, and have high oxidative …

[HTML][HTML] Resveratrol increase the proportion of oxidative muscle fiber through the AdipoR1-AMPK-PGC-1α pathway in pigs

Y Huang, Q Xia, Y Cui, Q Qu, Y Wei, Q Jiang - Journal of Functional Foods, 2020 - Elsevier
This study explored molecular mechanisms of resveratrol (RES) on regulating skeletal fiber-
type switching in pigs. RES had no effect on growth performance of pigs. Remarkably …