[HTML][HTML] Sexual minority stress and cellular aging in methamphetamine-using sexual minority men with treated HIV

D Ghanooni, AW Carrico, R Williams… - Psychosomatic …, 2022 - journals.lww.com
Objective Sexual minority men (eg, gay, bisexual, and other men who have sex with men)
experience stigma and sexual minority stress, which are theorized to drive negative health …

[HTML][HTML] Epigenetic clocks in relapse after a first episode of schizophrenia

ÀG Segura, L Prohens, G Mezquida, S Amoretti… - Schizophrenia, 2022 - nature.com
The main objective of the present study was to investigate the association between several
epigenetic clocks, covering different aspects of aging, with schizophrenia relapse evaluated …

[HTML][HTML] Epigenetic clock and methylation studies in vervet monkeys

AJ Jasinska, A Haghani, JA Zoller, CZ Li, A Arneson… - GeroScience, 2022 - Springer
DNA methylation-based biomarkers of aging have been developed for many mammals but
not yet for the vervet monkey (Chlorocebus sabaeus), which is a valuable non-human …

Genetic association between epigenetic aging-acceleration and the progression of mild cognitive impairment to Alzheimer's disease

H Liu, M Lutz, S Luo… - The Journals of …, 2022 - academic.oup.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder, and previous studies
have shown its association with accelerated aging. In this study, we hypothesized that single …

Metabolic reprogramming: a bridge between aging and tumorigenesis

S Drapela, D Ilter, AP Gomes - Molecular Oncology, 2022 - Wiley Online Library
Aging is the most robust risk factor for cancer development, with more than 60% of cancers
occurring in those aged 60 and above. However, how aging and tumorigenesis are …

A metabolomic aging clock using human cerebrospinal fluid

N Hwangbo, X Zhang, D Raftery, H Gu… - The Journals of …, 2022 - academic.oup.com
Quantifying the physiology of aging is essential for improving our understanding of age-
related disease and the heterogeneity of healthy aging. Recent studies have shown that, in …

[HTML][HTML] Utilization of host and microbiome features in determination of biological aging

K Ratiner, SK Abdeen, K Goldenberg, E Elinav - Microorganisms, 2022 - mdpi.com
The term 'old age'generally refers to a period characterized by profound changes in human
physiological functions and susceptibility to disease that accompanies the final years of a …

[HTML][HTML] Epigenetic clocks and their association with trajectories in perceived discrimination and depressive symptoms among US middle-aged and older adults

MA Beydoun, HA Beydoun, NN Hooten… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Background: Perceived discrimination may be associated with accelerated aging later in life,
with depressive symptoms acting as potential mediator. Methods: A nationally representative …

[HTML][HTML] Prenatal exposure to ambient air pollution and epigenetic aging at birth in newborns

AY Song, JI Feinberg, KM Bakulski, LA Croen… - Frontiers in …, 2022 - frontiersin.org
In utero air pollution exposure has been associated with adverse birth outcomes, yet effects
of air pollutants on regulatory mechanisms in fetal growth and critical windows of …

[HTML][HTML] Gestational age acceleration is associated with epigenetic biomarkers of prenatal physiologic stress exposure

V Euclydes, C Gomes, G Gouveia, VD Gastaldi… - Clinical …, 2022 - Springer
Background Physiological maternal stress response, such as imbalance in the
glucocorticoid pathway and immune system seems to be mediated by DNA methylation …