Analysis of single-cell microRNA is essential to reveal cell heterogeneity at the genetic level.
It raises a high demand for single-cell analytical methods because single-cell microRNA …

Mammalian germ cells stem from primordial germ cells (PGCs). Although the gene
regulatory network controlling the development of germ cells such as PGCs is critical for …

Early embryos undergo extensive epigenetic reprogramming to achieve gamete‐to‐embryo
transition, which involves the loading and removal of histone variant H2A. Z on chromatin …

Chenopodium quinoa is a crop with outstanding tolerance to saline soil, but long non-coding
RNAs (LncRNAs) expression profile driven by salt stress in quinoa has rarely been …

With the rapid advancement in sequencing technologies, the concept of omics has
revolutionized our understanding of cellular behaviors. Conventional omics investigation …

Anesthesia is unavoidable in surgical procedures. However, whether the general
anesthetics are neurotoxic to immature brains remains undefined. Neurodevelopmental …

The identification of differentially expressed genes between different cell groups is a crucial
step in analyzing single-cell RNA-sequencing (scRNA-seq) data. Even though various …

Although vitrification has been widely applied in assisted reproductive technology, it is
unknown whether storage time has any impact on the mRNA and lncRNA expression …

The pluripotent state of embryonic stem cells (ESCs) is regulated by a sophisticated network
of transcription factors. High expression of KLF17 has recently been identified as a hallmark …

Keratinocyte differentiation is an intricate process that is regulated by multiple mediators.
Using cultured human keratinocytes, we found that lysophosphatidic acid (LPA) induced the …