Chromatin dynamics through mouse preimplantation development revealed by single molecule localisation microscopy

M Portela, D Jimenez-Carretero, V Labrador… - Biology …, 2022 - journals.biologists.com
Most studies addressing chromatin behaviour during preimplantation development are
based on biochemical assays that lack spatial and cell-specific information, crucial during …

The transcriptional cell atlas of testis development in sheep at pre-sexual maturity

Y Wu, T Guo, J Li, C Niu, W Sun, S Zhu, H Zhao… - Current Issues in …, 2022 - mdpi.com
Sheep testes undergo a dramatic rate of development with structural changes during pre-
sexual maturity, including the proliferation and maturation of somatic niche cells and the …

Epigenetic regulation of cell fate transition: learning from early embryo development and somatic cell reprogramming

C Chen, Y Gao, W Liu, S Gao - Biology of Reproduction, 2022 - academic.oup.com
Epigenetic regulations play a central role in governing the embryo development and somatic
cell reprogramming. Taking advantage of recent advances in low-input sequencing …

Discoveries in pancreatic physiology and disease biology using single-cell RNA sequencing

H Fu, H Sun, H Kong, B Lou, H Chen, Y Zhou… - Frontiers in Cell and …, 2022 - frontiersin.org
Transcriptome analysis is used to study gene expression in human tissues. It can promote
the discovery of new therapeutic targets for related diseases by characterizing the endocrine …

Single‐cell profiling of transcriptomic changes during in vitro maturation of human oocytes

H Takeuchi, M Yamamoto, M Fukui… - Reproductive …, 2022 - Wiley Online Library
Purpose In vitro maturation (IVM) of human oocytes offers an invaluable opportunity for
infertility treatment. However, in vitro matured oocytes often show lower developmental …

[HTML][HTML] AHNAK2 is a biomarker and a potential therapeutic target of adenocarcinomas: AHNAK2 is a biomarker for adenocarcinomas

M Xu, A Cheng, L Yu, W Wei, J Li… - Acta Biochimica et …, 2022 - ncbi.nlm.nih.gov
Adenocarcinoma is the second largest histological type of cervical cancer, second only to
cervical squamous cell carcinoma. At present, despite the clinical treatment strategies of …

Coexpression network construction and visualization from transcriptomes underlying ER stress responses

DK Ko, F Brandizzi - Plant Proteostasis: Methods and Protocols, 2022 - Springer
Dynamic gene expression changes are primary cellular reactions in response to most
stresses and developmental cues in all organisms, including plants. With the ever …

Chromatin as a sensor of metabolic changes during early development

D Pladevall-Morera, JJ Zylicz - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Cellular metabolism is a complex network of biochemical reactions fueling development with
energy and biomass; however, it can also shape the cellular epigenome. Indeed, some …

EXOSC10/Rrp6 is essential for the eight-cell embryo/morula transition

FG Petit, SP Jamin, PY Kernanec, E Becker… - Developmental …, 2022 - Elsevier
Abstract The conserved 3′-5′ exoribonuclease EXOSC10/Rrp6 is required for
gametogenesis, brain development, erythropoiesis and blood cell enhancer function. The …

CHAF1b, chromatin assembly factor-1 subunit b, is essential for mouse preimplantation embryos

Y Zhang, Y Yang, P Qiao, X Wang, R Yu, H Sun… - International Journal of …, 2022 - Elsevier
Chromatin assembly factor-1, subunit b (CHAF1b), the p60 subunit of the chromatin-
assembly factor-1 (CAF-1) complex, is an evolutionarily conserved protein that has been …