Chronic heart failure is the end stage of cardiac diseases. With a high prevalence and a high
mortality rate worldwide, chronic heart failure is one of the heaviest health-related burdens …

COL1A1 is an important extracellular matrix component that is associated with poor
prognosis in cancers. In this study, As1411 aptamer-conjugated liposomes were used for …

Simple Summary Pediatric brain tumors represent a formidable challenge in the field of
oncology. Pediatric brain tumors are sub-classified into several molecular sub-types, where …

Viral infections are a great threat to human health. Currently, there are no effective vaccines
and antiviral drugs against the majority of viral diseases, suggesting the need to develop …

Electrospun fibers are versatile biomaterial platforms with great potential to support
regeneration. Electrospun fiber characteristics such as fiber diameter, degree of alignment …

Most therapies for treating sensorineural hearing loss are challenged by the delivery across
multiple tissue barriers to the hard-to-access anatomical location of the inner ear. In this …

Potato, the world's most popular crop is reported to provide a food source for nearly a billion
people. It is prone to a number of biotic stressors that affect yield and quality, out of which …

The global prevalence of diabetes mellitus was estimated to be 463 million people in 2019
and is predicted to rise to 700 million by 2045. The associated financial and societal costs of …

RNA interference (RNAi) has increased the possibility of restoring RNA drug targets for
cancer treatment. Small interfering RNA (siRNA) is a promising therapeutic RNAi tool that …