Vascular aging has a central role in the pathogenesis of cardiovascular diseases
contributing to increased mortality of older adults. There is increasing evidence that, in …

The ε4 allele of Apolipoprotein E (APOE), which is carried by approximately one out of six
individuals, remains the strongest known genetic risk factor for late-onset Alzheimer's …

We investigated the protective effect of young plasma on anesthesia-and surgery-induced
cognitive impairment and the potential underlying mechanism using bioinformatics …

摘要随着人口老龄化的日益严峻, 衰老及其带来的多种慢性疾病已成为亟待解决的社会问题.
综述了脑衰老发病的复杂生物学机制, 包括胶质细胞激活及炎症反应, 氧化应激损伤 …

There is converging evidence that young blood conveys cells, vesicles and molecules able
to revitalize function and restore organ integrity in old individuals. Here, we assessed the …

HIV-associated neurocognitive disorders (HAND) remain an unsolved problem that persists
despite using antiretroviral therapy. We have obtained data showing that HIV-gp120 protein …

AIM To determine whether limb remote ischemic post-conditioning (LRIC) protects against
high-intraocular-pressure (IOP)-induced retinal injury, and to identify underlying molecular …

Aging has become a serious social issue that places a heavy burden on society. However,
the underlying mechanisms of aging remain unclear. This study sought to understand the …

This paper provides a brief description of the components of umbilical-cord blood (CB). It
consider the application of CB and its components, more specifically, mesenchymal stem …

Purpose To investigate the in vivo neurofunctional changes and therapeutic effects of young
blood plasma (YBP) in aged mice, as well as the molecular mechanisms underlying the …