The multifaceted role of platelets in mediating brain function

T Burnouf, TL Walker - Blood, The Journal of the American …, 2022 - ashpublications.org
Platelets, the small, anucleate blood cells that originate from megakaryocytes in the bone
marrow, are typically associated with coagulation. However, it is now apparent that platelets …

Platelets in neurodegenerative conditions—friend or foe?

O Leiter, TL Walker - Frontiers in immunology, 2020 - frontiersin.org
It is now apparent that platelet function is more diverse than originally thought, shifting the
view of platelets from blood cells involved in hemostasis and wound healing to major …

Can the administration of platelet lysates to the brain help treat neurological disorders?

O Nebie, L Buée, D Blum, T Burnouf - Cellular and Molecular Life Sciences, 2022 - Springer
Neurodegenerative disorders of the central nervous system (CNS) and brain traumatic
insults are characterized by complex overlapping pathophysiological alterations …

[HTML][HTML] Platelets: the missing link between the blood and brain?

O Leiter, TL Walker - Progress in neurobiology, 2019 - Elsevier
It is becoming increasingly clear that interactions between the peripheral immune system
and the central nervous system are important in maintaining healthy brain function. Platelets …

Platelets as mediators of neuroinflammation and thrombosis

E Rawish, H Nording, T Münte, HF Langer - Frontiers in immunology, 2020 - frontiersin.org
Beyond platelets function in hemostasis, there is emerging evidence to suggest that platelets
contribute crucially to inflammation and immune responses. Therefore, considering the …

Platelets and neurovascular inflammation

HF Langer, T Chavakis - Thrombosis and haemostasis, 2013 - thieme-connect.com
Platelets participate in haemostasis and in thrombus formation in health and disease.
Moreover, they contribute to inflammation and cooperate with immune cells in a magnitude …

Platelets as modulators of cerebral ischemia/reperfusion injury

D Stegner, V Klaus, B Nieswandt - Frontiers in immunology, 2019 - frontiersin.org
Ischemic stroke is among the leading causes of disability and death worldwide. In acute
ischemic stroke, the rapid recanalization of occluded cranial vessels is the primary …

The role of platelets in the stimulation of neuronal synaptic plasticity, electric activity, and oxidative phosphorylation: possibilities for new therapy of neurodegenerative …

E Kopeikina, ED Ponomarev - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
The central nervous system (CNS) is highly vascularized where neuronal cells are located in
proximity to endothelial cells, astroglial limitans, and neuronal processes constituting …

Role of platelets in neurodegenerative diseases: a universal pathophysiology

M Behari, M Shrivastava - International Journal of Neuroscience, 2013 - Taylor & Francis
Platelets play an important role in a variety of disorders, namely, cardiovascular,
psychosomatic, psychiatric, thrombosis, HIV/AIDS in addition to various neurodegenerative …

[HTML][HTML] Alternative platelet activation pathways and their role in neurodegenerative diseases

P Ferrer-Raventós, K Beyer - Neurobiology of Disease, 2021 - Elsevier
Purpose of the review The study of platelets in the context of neurodegenerative diseases is
intensifying, and increasing evidence suggests that platelets may play an important role in …