We previously reported that the synergistically enhanced antimicrobial activity of magainin 2
(MG2a) and PGLa is related to membrane adhesion and fusion. Here, we demonstrate that …

We previously speculated that the synergistically enhanced antimicrobial activity of
Magainin 2 and PGLa is related to membrane adhesion, fusion, and further membrane …

We addressed the onset of synergistic activity of the two well-studied antimicrobial peptides
magainin 2 (MG2a) and PGLa using lipid-only mimics of Gram-negative cytoplasmic …

A synergistic enhancement of activities has been described for the amphipathic cationic
antimicrobial peptides magainin 2 and PGLa when tested in antimicrobial assays or in …

We studied the synergistic mechanism of equimolar mixtures of magainin 2 (MG2a) and
PGLa in phosphatidylethanolamine/phosphatidylglycerol mimics of Gram-negative …

Magainin 2 and PGLa are cationic, amphipathic antimicrobial peptides which when added
as equimolar mixture exhibit a pronounced synergism in both their antibacterial and pore …

Mixtures of the frog peptides magainin 2 and PGLa are well-known for their pronounced
synergistic killing of Gram-negative bacteria. We aimed to gain insight into the underlying …

Abstract PGLa and magainin 2 (MAG2) are amphiphilic antimicrobial peptides from frog skin
with known synergistic activity. The orientation of the two helices in membranes was studied …

To gain further insight into the antimicrobial activities of cationic linear peptides, we
investigated the topology of each of two peptides, PGLa and magainin 2, in oriented …

Biophysical and structural investigations are presented with a focus on the membrane lipid
interactions of cationic linear antibiotic peptides such as magainin, PGLa, LL37, and melittin …