Treatment strategies for HIV infection with emphasis on role of CRISPR/Cas9 gene: Success so far and road ahead
Advances in biotechnology have led to improving human health with number of novel
approaches to mitigate life-threatening diseases such as human immunodeficiency virus …
approaches to mitigate life-threatening diseases such as human immunodeficiency virus …
Modern biotechnology-based therapeutic approaches against HIV infection
The causative agent of acquired immune deficiency syndrome (AIDS) is human
immunodeficiency virus (HIV). Since its discovery before 30 years, a number of drugs known …
immunodeficiency virus (HIV). Since its discovery before 30 years, a number of drugs known …
Crispr-cas replacing antiviral drugs against hiv: An update
Various antiretroviral drugs do not kill or cure the human immunodeficiency virus (HIV) but
do prevent the replication of the virus. The combination of antiretroviral drugs is known as …
do prevent the replication of the virus. The combination of antiretroviral drugs is known as …
Gene Therapy with CRISPR/Cas9 Coming to Age for HIV Cure.
V Soriano - Aids Reviews, 2017 - search.ebscohost.com
The article focuses on the use of new gene-editing technologies, and especially the
CRISPR/Cas9 system for gene therapy research. It highlights the huge success of current …
CRISPR/Cas9 system for gene therapy research. It highlights the huge success of current …
HIV diagnosis and treatment through advanced technologies
Human immunodeficiency virus (HIV) is the chief contributor to global burden of disease. In
2010, HIV was the fifth leading cause of disability-adjusted life years in people of all ages …
2010, HIV was the fifth leading cause of disability-adjusted life years in people of all ages …
Current application of CRISPR/Cas9 gene-editing technique to eradication of HIV/AIDS
Z Huang, A Tomitaka, A Raymond, M Nair - Gene therapy, 2017 - nature.com
Human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) remains
a major health hazard despite significant advances in prevention and treatment of HIV …
a major health hazard despite significant advances in prevention and treatment of HIV …
The potential use of the CRISPR‐Cas system for HIV‐1 gene therapy
GDN Sanches-da-Silva, LFS Medeiros… - International journal of …, 2019 - Wiley Online Library
The HIV‐1 virus (human immunodeficiency virus) affects 36.9 million people worldwide, with
approximately 900000 deaths in 2017. The virus carrier can develop severe …
approximately 900000 deaths in 2017. The virus carrier can develop severe …
The therapeutic application of CRISPR/Cas9 technologies for HIV
Introduction: The use of antiretroviral therapy has led to a significant decrease in morbidity
and mortality in HIV-infected individuals. Nevertheless, gene-based therapies represent a …
and mortality in HIV-infected individuals. Nevertheless, gene-based therapies represent a …
Inducing CCR5Δ32/Δ32 homozygotes in the human Jurkat CD4+ cell line and primary CD4+ cells by CRISPR-Cas9 genome-editing technology
C Qi, D Li, X Jiang, X Jia, L Lu, Y Wang, J Sun… - … Therapy-Nucleic Acids, 2018 - cell.com
CC chemokine receptor type 5 (CCR5) is the main co-receptor for HIV entry into the target
CD4+ cells, and homozygous CCR5Δ32/Δ32 cells are resistant to CCR5-tropic HIV …
CD4+ cells, and homozygous CCR5Δ32/Δ32 cells are resistant to CCR5-tropic HIV …
Genome editing of the HIV co-receptors CCR5 and CXCR4 by CRISPR-Cas9 protects CD4+ T cells from HIV-1 infection
Background The main approach to treat HIV-1 infection is combination antiretroviral therapy
(cART). Although cART is effective in reducing HIV-1 viral load and controlling disease …
(cART). Although cART is effective in reducing HIV-1 viral load and controlling disease …