[HTML][HTML] RTS,S/AS01 malaria vaccine (Mosquirix®): a profile of its use

YY Syed - Drugs & Therapy Perspectives, 2022 - Springer
Abstract RTS, S/AS01 (Mosquirix®) is a vaccine against malaria caused by Plasmodium
falciparum. In a phase 3 trial, RTS, S/AS01 showed vaccine efficacy against clinical malaria …

RTS, S/AS01 vaccine (Mosquirix™): an overview

MB Laurens - Human vaccines & immunotherapeutics, 2020 - Taylor & Francis
Malaria is an illness caused by Plasmodium parasites transmitted to humans by infected
mosquitoes. Of the five species that infect humans, P. falciparum exacts the highest toll in …

Mosquirix (RTS, S): a novel vaccine for the prevention of Plasmodium falciparum malaria

KJ Wilby, TTY Lau, SE Gilchrist… - Annals of …, 2012 - journals.sagepub.com
Objective: To summarize and evaluate the literature for Mosquirix (RTS, S) and provide
insight into the therapeutic and economic controversies of this novel malaria vaccine …

[HTML][HTML] Mosquirix™ RTS, S/AS01 vaccine development, immunogenicity, and efficacy

AY Nadeem, A Shehzad, SU Islam, EA Al-Suhaimi… - Vaccines, 2022 - mdpi.com
Malaria is a parasitic infection caused by bites from Plasmodium falciparum (P. falciparum)-
infected mosquitoes with a present scale of symptoms ranging from moderate fever to …

[HTML][HTML] Safety, Immunogenicity and Duration of Protection of the RTS,S/AS02D Malaria Vaccine: One Year Follow-Up of a Randomized Controlled Phase I/IIb Trial

P Aide, JJ Aponte, M Renom, T Nhampossa… - PLoS …, 2010 - journals.plos.org
Background The RTS, S/AS02D vaccine has been shown to have a promising safety profile,
to be immunogenic and to confer protection against malaria in children and infants. Methods …

[HTML][HTML] Implementation strategies for the introduction of the RTS, S/AS01 (RTS, S) malaria vaccine in countries with areas of highly seasonal transmission: workshop …

CS Merle - Malaria journal, 2023 - Springer
A workshop on implementation strategies for the introduction of the RTS, S/AS01 (RTS, S)
malaria vaccine in countries with areas of highly seasonal transmission, was held as a …

Safety and immunogenicity of the RTS, S/AS02A candidate malaria vaccine in children aged 1–4 in Mozambique

E Macete, JJ Aponte, C Guinovart… - Tropical Medicine & …, 2007 - Wiley Online Library
Background The development of a malaria vaccine remains a public health priority for sub‐
Saharan Africa. RTS, S/AS02A candidate malaria vaccine has been shown to be safe and …

[HTML][HTML] Malaria vaccines: progress to date

DI Stanisic, MF Good - BioDrugs, 2023 - Springer
Malaria is a mosquito-borne disease caused by protozoan parasites of the genus
Plasmodium. Despite significant declines in malaria-attributable morbidity and mortality over …

[HTML][HTML] Assessing the safety, impact and effectiveness of RTS,S/AS01E malaria vaccine following its introduction in three sub-Saharan African countries …

N Praet, KP Asante, MC Bozonnat, EJ Akité, PO Ansah… - Malaria Journal, 2022 - Springer
Background Following a 30-year development process, RTS, S/AS01E (GSK, Belgium) is
the first malaria vaccine to reach Phase IV assessments. The World Health Organization …

Clinical development of RTS, S/AS malaria vaccine: a systematic review of clinical Phase I–III trials

ST Agnandji, JF Fernandes, EB Bache… - Future …, 2015 - Taylor & Francis
The first clinical Phase III trial evaluating a malaria vaccine was completed in December
2013 at 11 sites from seven sub-Saharan African countries. This systematic review assesses …