Selenium-N-heterocyclic carbene (Se-NHC) complexes with higher aromaticity inhibit microbes: synthesis, structure, and biological potential

A Kamal, MA Iqbal, HN Bhatti… - Journal of Coordination …, 2022 - Taylor & Francis
The synthesis of five selenium complexes bearing imidazole-based N-heterocyclic carbene
ligands (Se-NHC) are reported. The adducts were characterized by elemental and …

Biological potential of vinyl/allyl substituted imidazole-based N-heterocyclic carbene adducts: synthesis, spectral and X-ray crystallographic structural characteristics

A Kamal, AH Ibrahim, SS Al-Rawi, MA Iqbal, HN Bhatti - Chemical Papers, 2024 - Springer
This manuscript describes the synthesis of three new selenium vinyl/allyl adducts (IV–VI),
which incorporate imidazolium-N-heterocyclic carbene salts (I–III) are. The characterization …

Green synthesis of selenium-N-heterocyclic carbene compounds: Evaluation of antimicrobial and anticancer potential

A Kamal, M Nazari, M Yaseen, MA Iqbal… - Bioorganic …, 2019 - Elsevier
Three benzimidazolium salts (III-V) and respective selenium adducts (VI-VIII) were designed,
synthesized and characterized by various analytical techniques (FT-IR and NMR 1 H, 13 C) …

N-heterocyclic carbene based Bi-nuclear organoselenium compounds impart a mild biocidal potential compared to their ligands: Synthesis, characterization …

A Hassan, MA Iqbal, HN Bhatti, M Shahid - Computational Biology and …, 2023 - Elsevier
N-heterocyclic carbene (NHC) based compounds are remarkably known for astonishing
biological potentials. Coordination of metal center with these compounds can substantially …

Cytotoxic, Thrombolytic and Antibacterial Evaluation of Synthesized Substituted and Un-Substituted Selenium-N-Heterocyclic Carbene Adducts.

A Kamal, MA Iqbal, HN Bhatti… - Journal of the Chemical …, 2023 - search.ebscohost.com
Alkyl-substituted azolium salts (1-8) and their Se-N-heterocyclic carbene (Se-N-Het-C)
adducts (9-12) were obtained in very reasonable yields. All synthesized azolium salts and …

Bioactivity and DNA/BSA interactions of selenium N‐heterocyclic carbene adducts

R Ashraf, MA Iqbal, HN Bhatti, MRSA Janjua… - …, 2020 - Wiley Online Library
In wake of promising biomedical applications of organo‐selenium compounds, the present
work was planned to synthesize selenium adducts (1 s‐‐4 s) and their respective azolium …

O-Halogen-substituted arene linked selenium-N-heterocyclic carbene compounds induce significant cytotoxicity: Crystal structures and molecular docking studies

K Hayat, M Shkeel, MA Iqbal, CK Quah… - Journal of …, 2023 - Elsevier
Synthesis of N-arylated benzimidazolium salts 1–2, as stable N-heterocyclic Carbene (NHC)
σ-donor ligands, was carried out by simple, facile and high yielding method. Respective Se …

Green synthesis of mono-and di-selenium-N-heterocyclic carbene adducts: Characterizations, crystal structures and pro-apoptotic activities against human colorectal …

MA Iqbal, RA Haque, WC Ng, LEH Hassan… - Journal of …, 2016 - Elsevier
From mono-and bis-benzimidazolium salts, three new Se–NHC adducts were synthesized
using water as a solvent. Single crystals analyses indicated that crystal structures of Se …

Green synthesis of selenium based N-heterocyclic carbene compounds; structural, in-vitro anticancer and molecular docking studies

K Hayat, U Tariq, QA Wong, CK Quah… - … Biology and Chemistry, 2021 - Elsevier
Abstract Benzimidazolium salts (3− 6) were synthesized as stable N-Heterocyclic Carbene
(NHC) precursors and their selenium-NHC compounds/Selenones (7− 10) were prepared …

Synthesis, characterization and molecular docking of benz-imidazolium Se-adducts: Antimicrobial and anticancer studies

A Hassan, R Ashraf, MA Iqbal, M El-Naggar… - Journal of Molecular …, 2024 - Elsevier
N-heterocyclic carbene (NHC) based compounds are remarkably known for astonishing
biological potentials. Coordination of metal center with these compounds could substantially …