Gut permeability and its clinical relevance in schizophrenia

I Ishida, J Ogura, E Aizawa, M Ota… - …, 2022 - Wiley Online Library
Aim We aimed to examine the gut permeability in patients with schizophrenia and its
relevance to schizophrenia symptoms, medication, cognitive functions, and blood immune …

Altered intestinal permeability biomarkers in schizophrenia: a possible link with subclinical inflammation

K Gokulakrishnan, J Nikhil, S Vs… - Annals of …, 2022 - journals.sagepub.com
Background and Purpose Emerging studies have shown that gut-derived endotoxins might
play a role in intestinal and systemic inflammation. Although the significance of intestinal …

[HTML][HTML] The deficit subtype of schizophrenia is associated with a pro-inflammatory phenotype but not with altered levels of zonulin: Findings from a case-control study

A Cyran, E Pawlak, P Piotrowski, T Bielawski… - …, 2023 - Elsevier
There is evidence that subclinical inflammation and increased gut permeability might be
involved in the pathophysiology of schizophrenia. Less is known about these phenomena in …

Association between gut permeability, brain volume, and cognition in healthy participants and patients with schizophrenia spectrum disorder

TAW Scheurink, J Borkent, SS Gangadin… - Brain and …, 2023 - Wiley Online Library
Introduction The barrier function of the gut is important for many organs and systems,
including the brain. If gut permeability increases, bacterial fragments may enter the …

The differences between gluten sensitivity, intestinal biomarkers and immune biomarkers in patients with first-episode and chronic schizophrenia

M Dzikowski, D Juchnowicz, I Dzikowska… - Journal of Clinical …, 2020 - mdpi.com
Schizophrenia is a heterogeneous disorder without a fully elucidated etiology and
mechanisms. One likely explanation for the development of schizophrenia is low-grade …

Intestinal permeability and its significance in psychiatric disorders–a narrative review and future perspectives

J Wasiak, O Gawlik-Kotelnicka - Behavioural Brain Research, 2023 - Elsevier
The topic of increased intestinal permeability and its impact on the human body is.
increasingly being addressed by researchers. It is associated with disruption of the …

Gut microbiome and magnetic resonance spectroscopy study of subjects at ultra-high risk for psychosis may support the membrane hypothesis

Y He, T Kosciolek, J Tang, Y Zhou, Z Li, X Ma… - European …, 2018 - cambridge.org
Background: The microbiota-gut-brain axis and membrane dysfunction in the brain has
attracted increasing attention in the field of psychiatric research. However, the possible …

Elevated systemic levels of markers reflecting intestinal barrier dysfunction and inflammasome activation are correlated in severe mental illness

SB Jensen, MA Sheikh, IA Akkouh, A Szabo… - Schizophrenia …, 2023 - academic.oup.com
Abstract Background and Hypothesis Gut microbiota alterations have been reported in
severe mental illness (SMI) but fewer studies have probed for signs of gut barrier disruption …

Involvement of gut microbiota in schizophrenia and treatment resistance to antipsychotics

M Manchia, A Fontana, C Panebianco, P Paribello… - Biomedicines, 2021 - mdpi.com
The gut microbiota is constituted by more than 40,000 bacterial species involved in key
processes including high order brain functions. Altered composition of gut microbiota has …

[PDF][PDF] The brain-gut axis dysfunctions and hypersensitivity to food antigens in the etiopathogenesis of schizophrenia

H Karakuła-Juchnowicz, M Dzikowski… - Psychiatr …, 2016 - scholar.archive.org
Despite over 100-year history of research on schizophrenia, its etiology is still not fully
understood, which might be due to the significant heterogeneity in terms of both its course …