Evaluation of in vitro and in silico anti-inflammatory potential of some selected medicinal plants of Bangladesh against cyclooxygenase-II enzyme

MA Islam, MNH Zilani, P Biswas, DA Khan… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Medicinal plants are sources of chemical treasures that
can be used in treatment of different diseases, including inflammatory disorders …

Computational screening of potential anti-inflammatory leads from Jeevaneeya Rasayana plants targeting COX-2 and 5-LOX by molecular docking and dynamic …

KN Hemavathi, S Skariyachan, R Raju… - Computers in Biology …, 2024 - Elsevier
Inflammation plays a pivotal role in various pathological processes, ranging from routine
injuries and infections to cancer. Cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) …

[PDF][PDF] In silico docking studies on the components of inonotus sp., a medicinal mushroom against cyclooxygenase-2 enzyme

SS Meenambiga, K Rajagopal, R Durga - Asian J Pharm Clin Res, 2015 - researchgate.net
Objective: Inonotusspp., the mushroom is widely present and known for its medicinal
property. This mushroom produces several bioactive compounds with various …

Synthesis, biological evaluation, molecular docking and theoretical evaluation of ADMET properties of nepodin and chrysophanol derivatives as potential …

J Grover, V Kumar, V Singh, K Bairwa… - European journal of …, 2014 - Elsevier
Nepodin and chrysophanol, isolated from Rumex nepalensis roots, showed significant
cyclooxygenase (COX) inhibitory activity. To further optimize these lead molecules and study …

[PDF][PDF] ANTI-INFLAMMATORY ACTIVITY OF STEM BARK DICHLOROMETHANE FRACTION Syzygium samarangense EXTRACT AS COX-2 INHIBITOR: A …

AM Sururi, M Raihan, ER Aisa, FN Safitri… - Jurnal Kimia …, 2022 - e-journal.unair.ac.id
Syzygium samarangense is a plant that is rich in flavonoid compounds. Previous research
revealed that the dichloromethane fraction from the stem bark extract contained four …

[HTML][HTML] Evaluation of anti-inflammatory activity of selected medicinal plants used in Indian traditional medication system in vitro as well as in vivo

RU Shaikh, MM Pund, RN Gacche - Journal of traditional and …, 2016 - Elsevier
The present study was carried out to evaluate in vivo and in vitro anti-inflammatory potential
of selected medicinal plants used in Indian traditional medication. The sequentially extracted …

Exploring molecular docking with MM-GBSA and molecular dynamics simulation to predict potent inhibitors of cyclooxygenase (COX-2) enzyme from terpenoid-based …

A Nayak, A Gadnayak, KT Dash, S Jena… - Journal of …, 2023 - Taylor & Francis
Abstract Cyclooxygenase 2 (COX-2), the key enzyme involved in prostaglandin (PGs)
production, is known to take part in inflammatory and immune responses. Though COX-2 …

[PDF][PDF] In silico molecular docking studies of lichen metabolites against cyclooxygenase-2 enzyme

MF Khan, SA Nabila, RB Rashid… - Bangladesh …, 2015 - academia.edu
Abstract Cyclooxygenase-2 (COX-2) is an inducible enzyme that causes inflammation. COX-
2 inhibitors are clinically effective anti-inflammatory agents with less gastrointestinal and …

Identification of promising compounds from curry tree with cyclooxygenase inhibitory potential using a combination of machine learning, molecular docking, dynamics …

PN Pandya, SP Kumar, K Bhadresha… - Molecular …, 2020 - Taylor & Francis
ABSTRACT Murraya koenigii (Linn.) Spreng, commonly known as curry leaf tree, is popular
as a condiment and spice among Asian countries. Ethnobotanical studies suggest that …

Screening cyclooxygenase-2 inhibitors from Allium sativum L. compounds: in silico approach

M Sadeghi, M Miroliaei, F Fateminasab… - Journal of Molecular …, 2022 - Springer
Inflammation is a natural protective response toward various simulators, including tissue
damage or pathogens. The cyclooxygenase-2 (COX-2) is a very important protein in …