Preparation of oral solid dosage forms based on homogenized spot melting technique

S Wei, L Shen, X Xu, W Shan, Y Yang - International Journal of …, 2022 - Elsevier
Given the benefits of high printing precision and capability, the selective laser sintering
technique has been used to manufacture medicines and implants with unique engineering …

Oral preparations with tunable dissolution behavior based on selective laser sintering technique

Y Yang, Y Xu, S Wei, W Shan - International Journal of Pharmaceutics, 2021 - Elsevier
Selective laser sintering (SLS) sinters a powder layer by layer with a laser beam to prepare
3D printlets, which are widely used in the field of tissue engineering and personalized …

Melt milling as manufacturing method for solid crystalline suspensions

P da Igreja, A Erve, M Thommes - European Journal of Pharmaceutics and …, 2021 - Elsevier
Abstract Production of submicron particles (0.1–1 μm) has been identified by the
pharmaceutical industry as a key technology to enhance the bioavailability of poorly water …

[PDF][PDF] Hot-melt extrusion and prilling as contemporary and promising techniques in the solvent free production of solid oral dosage forms, based on solid dispersions

A Aleksovski, C Vervaet, R Dreu - Maced Pharm Bull, 2016 - academia.edu
Hot melt extrusion and prilling are gaining importance as solvent free and continuous
techniques in the production of solid oral dosage forms with added value, by incorporating …

Synergistic application of twin-screw granulation and selective laser sintering 3D printing for the development of pharmaceutical dosage forms with enhanced …

R Thakkar, Y Zhang, J Zhang… - European Journal of …, 2021 - Elsevier
This study demonstrated the first case of combining a novel continuous granulation
technique with powder-bed fusion-based selective laser sintering (SLS) process to enhance …

Selective laser sintering 3-dimensional printing as a single step process to prepare amorphous solid dispersion dosage forms for improved solubility and dissolution …

DA Davis Jr, R Thakkar, Y Su, RO Williams III… - Journal of …, 2021 - Elsevier
This study reports the development of ritonavir-copovidone amorphous solid dispersions
(ASDs) and dosage forms thereof using selective laser sintering (SLS) 3-dimensional (3-D) …

[PDF][PDF] Hot melt extruded and injection moulded dosage forms: recent research and patents

I Major, C McConville - Recent Pat Drug Deliv Formul, 2015 - academia.edu
Hot Melt Extrusion (HME) and Injection Moulding (IM) are becoming more prevalent in the
drug delivery field due to their continuous nature and advantages over current …

Hot-melt 3D extrusion for the fabrication of customizable modified-release solid dosage forms

J Lee, C Song, I Noh, S Song, YS Rhee - Pharmaceutics, 2020 - mdpi.com
In this work, modified-release solid dosage forms were fabricated by adjusting geometrical
properties of solid dosage forms through hot-melt 3D extrusion (3D HME). Using a 3D printer …

Recent Progress in Hot Melt Extrusion Technology in Pharmaceutical Dosage Form Design

S Salave, K Prayag, D Rana, P Amate… - Recent Advances in …, 2022 - ingentaconnect.com
Background: The Hot Melt Extrusion (HME) technique has shown tremendous potential in
transforming highly hydrophobic crystalline drug substances into amorphous solids without …

Melt processes for oral solid dosage forms

TW Wong, PWS Heng - Encyclopedia of pharmaceutical …, 2013 - api.taylorfrancis.com
The design of pharmaceutical solid dosage form using meltable materials has become
increasingly popular as alternative special processes to avoid aqueous or organic solvents …