Malaria parasites are less vulnerable to mosquito immune responses once ookinetes
transform into oocysts, facilitating parasite development in the mosquito. However, the …

The circumsporozoite protein, CSP, is the major surface protein of Plasmodium sporozoites,
the form of malaria parasites transmitted by mosquitoes. CSP is involved in sporozoite …

Although the ability of mosquitoes to limit Plasmodium infection is well documented, many
questions remain as to how malaria parasites are recognized and killed by the mosquito …

Plasmodium sporozoites make a remarkable journey from the mosquito midgut to the
mammalian liver. The sporozoite's major surface protein, circumsporozoite protein (CSP), is …

An essential requisite for transmission of Plasmodium, the causative agent of malaria, is the
successful completion of a complex developmental cycle in its mosquito vector. Of hundreds …

The circumsporozoite protein (CSP) is the major surface protein of malaria sporozoites
(SPZs), the motile and invasive parasite stage inoculated in the host skin by infected …

Plasmodium sporozoites are the highly motile and invasive forms of the malaria parasite
transmitted by mosquitoes. Sporozoites form within oocysts at the midgut wall of the …

Background The circumsporozoite protein is the most abundant polypeptide expressed by
sporozoites, the malaria parasite stage capable of infecting humans. Sporozoite invasion of …

After being ingested by a female Anopheles mosquito during a bloodmeal on an infected
host, and before they can reach the mosquito salivary glands to be transmitted to a new host …

Background There is emerging evidence that mosquito anti-Plasmodium immunity is
multimodal with distinct mechanisms for killing malaria parasites at either the ookinete or …