Gene–environment interaction using polygenic scores: Do polygenic scores for psychopathology moderate predictions from environmental risk to behavior problems?

R Plomin, A Gidziela, M Malanchini… - Development and …, 2022 - cambridge.org
The DNA revolution has energized research on interactions between genes and
environments (GxE) by creating indices of G (polygenic scores) that are powerful predictors …

Candidate gene–environment interaction research: Reflections and recommendations

DM Dick, A Agrawal, MC Keller… - Perspectives on …, 2015 - journals.sagepub.com
Studying how genetic predispositions come together with environmental factors to contribute
to complex behavioral outcomes has great potential for advancing the understanding of the …

Gene–environment correlation in developmental psychopathology

A Knafo, SR Jaffee - Development and psychopathology, 2013 - cambridge.org
Modern research acknowledges that psychopathology and individual differences in normal
development are the joint products of both biological and social influences. Although there …

Gene–environment interactions in genome‐wide association studies: current approaches and new directions

SJ Winham, JM Biernacka - Journal of Child Psychology and …, 2013 - Wiley Online Library
Background Complex psychiatric traits have long been thought to be the result of a
combination of genetic and environmental factors, and gene–environment interactions are …

Commentary: Missing heritability, polygenic scores, and gene–environment correlation

R Plomin - Journal of Child Psychology and Psychiatry, 2013 - Wiley Online Library
This special issue amply fulfils its aim of moving the study of gene× environment (GE)
interplay forward constructively and creatively, exploiting contributions from diverse …

Youth appraisals of inter-parental conflict and genetic and environmental contributions to attention-deficit hyperactivity disorder: Examination of GxE effects in a twin …

M Nikolas, KL Klump, SA Burt - Journal of abnormal child psychology, 2012 - Springer
Identification of gene x environment interactions (GxE) for attention-deficit hyperactivity
disorder (ADHD) is a crucial component to understanding the mechanisms underpinning the …

Gene–environment interaction

D Cicchetti - Development and Psychopathology, 2007 - cambridge.org
This Special Issue of Development and Psychopathology is devoted to the topic of gene–
environment interaction (G x E) and developmental psychopathology. GxE, one of several …

Environmental susceptibility for all: A data-driven approach suggests individual differences in domain-general and domain-specific patterns of environmental …

N Markovitch, Y Hart, A Knafo-Noam - Development and …, 2023 - cambridge.org
How we are influenced by our environment is a fundamental question in developmental
science. Theories and empirical research have claimed that some individuals are …

Widespread covariation of early environmental exposures and trait-associated polygenic variation

E Krapohl, LJ Hannigan, JB Pingault… - Proceedings of the …, 2017 - National Acad Sciences
Although gene–environment correlation is recognized and investigated by family studies
and recently by SNP-heritability studies, the possibility that genetic effects on traits capture …

Gene–environment interplay and psychopathology: Multiple varieties but real effects

M Rutter, TE Moffitt, A Caspi - Journal of child Psychology and …, 2006 - Wiley Online Library
Gene–environment interplay is a general term that covers several divergent concepts with
different meanings and different implications. In this review, we evaluate research evidence …