[HTML][HTML] A computational design of siRNA in SARS-CoV-2 spike glycoprotein gene and its binding capability toward mRNA

AA Parikesit, ANM Ansori… - Indonesian Journal of …, 2022 - journal.ugm.ac.id
COVID-19 pandemic has no immediate ending in sight, and any significant increasing cases
were observed worldwide. Currently, there are only two main strategies for developing …

[HTML][HTML] In silico identification of characteristics spike glycoprotein of SARS-CoV-2 in the development novel candidates for COVID-19 infectious diseases

TM Fakih, ML Dewi - Journal of Biomedicine and Translational …, 2020 - ejournal2.undip.ac.id
Background: The emergence of infectious diseases caused by SARS-CoV-2 has resulted in
more than 90,000 infections and 3,000 deaths. The coronavirus spike glycoprotein …

[HTML][HTML] In silico prediction of siRNA to silence the SARS-CoV-2 omicron variant targeting BA. 4, BA. 5, BQ. 1, BQ1. 1. and XBB: an alternative to traditional …

R Islam, A Shahriar, N Fatema, MR Uddin… - Future Journal of …, 2023 - Springer
Background After the first infection in December 2019, the mutating strains of SARS-CoV2
have already affected a lot of healthy people around the world. But situations have not been …

[HTML][HTML] In silico prediction and experimental evaluation of potential siRNAs against SARS-CoV-2 inhibition in Vero E6 cells

SS Sohrab, SA El-Kafrawy, EI Azhar - Journal of King Saud University …, 2022 - Elsevier
Objective The acute cases of pneumonia (COVID-19) were first reported from China in
December 2019, and the pathogen was identified as SARS-CoV-2. Currently, many …

[HTML][HTML] A computational approach to design potential siRNA molecules as a prospective tool for silencing nucleocapsid phosphoprotein and surface glycoprotein …

UF Chowdhury, MUS Shohan, KI Hoque, MA Beg… - Genomics, 2021 - Elsevier
An outbreak, caused by an RNA virus, SARS-CoV-2 named COVID-19 has become
pandemic with a magnitude which is daunting to all public health institutions in the absence …

[HTML][HTML] In silico molecular docking of SARS-CoV-2 surface proteins with microbial non-ribosomal peptides: Identification of potential drugs

P Bansal, R Kumar, J Singh, S Dhanda - Journal of Proteins and …, 2021 - Springer
Outbreak of COVID-19 by SARS-CoV-2 infection caused severe acute respiratory syndrome
that has been declared a public health emergency of international concern. To control …

[HTML][HTML] In-silico drug designing of spike receptor with its ACE2 receptor and Nsp10/Nsp16 mtase complex against SARS-CoV-2

MA Siddiqa, DS Rao, G Suvarna… - International Journal of …, 2021 - Springer
Abstract The realm Riboviria constitutes Coronaviruses, which led to the emergence of the
pandemic COVID 19 in the twenty-first century affected millions of lives. At present, the …

Computational design of a potential therapeutic peptide against spike protein of SARS-CoV-2

A Alibakhshi, S Ahangarzadeh… - Journal of …, 2021 - World Scientific
SARS-CoV-2 entrance to the host cells is started by the interaction between receptor binding
domain (RBD) of the spike (S) protein on the virus with the angiotensin-converting enzyme 2 …

[HTML][HTML] Molecular modeling of natural and synthesized inhibitors against SARS-CoV-2 spike glycoprotein

M Jomhori, H Mosaddeghi - Research on Biomedical Engineering, 2021 - Springer
Purpose Viral diseases increasingly endanger the world public health because of the
transient efficacy of antiviral therapies. The novel coronavirus disease 2019 (COVID-19) has …

[HTML][HTML] Screening of inhibitors against SARS-CoV-2 spike protein and their capability to block the viral entry mechanism: A viroinformatics study

AEA Farouk, MH Baig, MI Khan, T Park… - Saudi journal of …, 2021 - Elsevier
Abstract SARS-CoV-2, previously named 2019 novel coronavirus (2019-nCoV), has been
associated with the global pandemic of acute respiratory distress syndrome. First reported in …