Gut–microbiota–brain axis in the vulnerability to psychosis in adulthood after repeated cannabis exposure during adolescence

X Wan, A Eguchi, Y Qu, Y Yang, L Chang… - European Archives of …, 2022 - Springer
Increasing epidemiological evidence shows that the use of cannabis during adolescence
could increase the risk for psychosis in adulthood. However, the precise mechanisms …

An integrative study of the microbiome gut-brain-axis and hippocampal inflammation in psychosis: persistent effects from mode of birth

P Joe, JC Clemente, E Piras, DS Wallach… - Schizophrenia …, 2022 - Elsevier
The mechanism producing psychosis appears to include hippocampal inflammation, which
could be associated with the microbiome-gut-brain-axis (MGBS). To test this hypothesis we …

Dysregulation of microbiota in patients with first-episode psychosis is associated with symptom severity and treatment response

P Sen, E Prandovszky, JK Honkanen, O Chen… - Biological …, 2024 - Elsevier
Background The gut microbiome has been implicated in the pathogenesis of mental
disorders where the gut-brain axis acts as a bidirectional communication network. Methods …

The independent and combined effects of cannabis use and systemic inflammation during the early stages of psychosis: exploring the two-hit hypothesis

F Corsi-Zuelli, L Marques, DL Da Roza… - Psychological …, 2022 - cambridge.org
Background Cannabis consumption is a modifiable risk factor associated with psychosis, but
not all cannabis users develop psychosis. Animal studies suggest that an antecedent active …

Gut microbiome and magnetic resonance spectroscopy study of subjects at ultra-high risk for psychosis may support the membrane hypothesis

Y He, T Kosciolek, J Tang, Y Zhou, Z Li, X Ma… - European …, 2018 - cambridge.org
Background: The microbiota-gut-brain axis and membrane dysfunction in the brain has
attracted increasing attention in the field of psychiatric research. However, the possible …

Enduring neurobehavioral effects induced by microbiota depletion during the adolescent period

G Lach, C Fülling, TFS Bastiaanssen, F Fouhy… - Translational …, 2020 - nature.com
The gut microbiota is an essential regulator of many aspects of host physiology. Disruption
of gut microbial communities affects gut-brain communication which ultimately can manifest …

The connection between microbiome and schizophrenia

B Golofast, K Vales - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
There has been an accumulation of knowledge about the human microbiome, some detailed
investigations of the gastrointestinal microbiota and its functions, and the highlighting of …

Transplantation of fecal microbiota from patients with alcoholism induces anxiety/depression behaviors and decreases brain mGluR1/PKC ε levels in mouse

W Zhao, Y Hu, C Li, N Li, S Zhu, X Tan, M Li… - Biofactors, 2020 - Wiley Online Library
Recent studies have revealed that the gut microbiota participates in the psychiatric behavior
changes in disorders associated with alcohol. But it still remains unknown whether …

Gut Microbiota Taxon-Dependent Transformation of Microglial M1/M2 Phenotypes Underlying Mechanisms of Spatial Learning and Memory Impairment after Chronic …

Y Wu, Z Dong, X Jiang, L Qu, W Zhou, X Sun… - Microbiology …, 2023 - Am Soc Microbiol
Methamphetamine (METH) exposure may lead to cognitive impairment. Currently, evidence
suggests that METH exposure alters the configuration of the gut microbiota. However, the …

Gut microbiome: a brief review on its role in schizophrenia and first episode of psychosis

K Tsamakis, S Galinaki, E Alevyzakis, I Hortis… - Microorganisms, 2022 - mdpi.com
There is a growing body of evidence highlighting the role of gut microbiota as a biological
basis of psychiatric disorders. The existing literature suggest that cognitive and emotional …