Genomic analyses in cancer have been enormously impactful, leading to the identification of
driver mutations and development of targeted therapies. But the functions of the vast majority …

Cancer genomics research aims to advance personalized oncology by finding and targeting
specific genetic alterations associated with cancers. In genome-driven oncology, treatments …

When it comes to precision oncology, proteogenomics may provide better prospects to the
clinical characterization of tumors, help make a more accurate diagnosis of cancer, and …

The concept of personalized medicine is predominantly been pursued through genomic and
transcriptomic technologies, leading to the identification of multiple mutations in a large …

The complexities of tumor genomes are rapidly being uncovered, but how they are regulated
into functional proteomes remains poorly understood. Standard proteomics workflows use …

The quest to decipher protein alterations in cancer has spanned well over half a century.
The vast dynamic range of protein abundance coupled with a plethora of isoforms and …

With the human genome sequence now determined, the field of molecular medicine is
moving beyond genomics to proteomics. In the field of cancer research, the key question is …

The emergence of novel technologies allows researchers to facilitate the comprehensive
analyses of genomes, transcriptomes, and proteomes in health and disease. The …

The National Cancer Institute (NCI) Clinical Proteomic Tumor Analysis Consortium is
applying the latest generation of proteomic technologies to genomically annotated tumors …

The dawn of the post‐genome era is leading to extraordinary opportunities in biomedicine.
Our group has embarked on a major effort to integrate genomics, transcriptomics and …