Neural noise is associated with age-related neural dedifferentiation

RE Pichot, DJ Henreckson, M Foley, JD Koen - bioRxiv, 2022 - biorxiv.org
Age-related neural dedifferentiation–reductions in the selectivity and precision of neural
representations–contributes to cognitive aging and is thought to result from age increases in …

Linked sources of neural noise contribute to age-related cognitive decline

TT Tran, CE Rolle, A Gazzaley… - Journal of cognitive …, 2020 - direct.mit.edu
Healthy aging is associated with a multitude of structural changes in the brain. These
physical age-related changes are accompanied by increased variability in neural activity of …

Dissociative effects of age on neural differentiation at the category and item levels

S Srokova, ANZ Aktas, JD Koen… - Journal of …, 2024 - Soc Neuroscience
Increasing age is associated with age-related neural dedifferentiation, a reduction in the
selectivity of neural representations, which has been proposed to contribute to cognitive …

[PDF][PDF] Age-related declines in neural selectivity manifest differentially during encoding and recognition

C Pauleya, VR Sommera, M Kobeltc, A Keresztesd… - scholar.archive.org
One important factor contributing to age-related memory decline is the loss of distinctiveness
with which information is represented in brain activity. This loss in neural selectivity may be …

Early visual cortices reveal interrelated item and category representations in aging

C Pauley, A Karlsson, MC Sander - Eneuro, 2024 - eneuro.org
Neural dedifferentiation, the finding that neural representations tend to be less distinct in
older adults compared with younger adults, has been associated with age-related declines …

Neural distinctiveness declines with age in auditory cortex and is associated with auditory GABA levels

P Lalwani, H Gagnon, K Cassady, M Simmonite… - NeuroImage, 2019 - Elsevier
Neural activation patterns in the ventral visual cortex in response to different categories of
visual stimuli (eg, faces vs. houses) are less selective, or distinctive, in older adults than in …

Neural differentiation is moderated by age in scene-selective, but not face-selective, cortical regions

S Srokova, PF Hill, JD Koen, DR King, MD Rugg - ENeuro, 2020 - eneuro.org
The aging brain is characterized by neural dedifferentiation, an apparent decrease in the
functional selectivity of category-selective cortical regions. Age-related reductions in neural …

[HTML][HTML] Age-related delay in visual and auditory evoked responses is mediated by white-and grey-matter differences

D Price, LK Tyler, R Neto Henriques… - Nature …, 2017 - nature.com
Slowing is a common feature of ageing, yet a direct relationship between neural slowing and
brain atrophy is yet to be established in healthy humans. We combine …

Age differences in neural distinctiveness revealed by multi-voxel pattern analysis

J Carp, J Park, TA Polk, DC Park - Neuroimage, 2011 - Elsevier
Current theories of cognitive aging argue that neural representations become less distinctive
in old age, a phenomenon known as dedifferentiation. The present study used multi-voxel …

Neural noise in the age-varying human brain predicts perceptual decisions

L Waschke, M Woestmann, J Obleser - bioRxiv, 2017 - biorxiv.org
Humans sometimes do perceive differences where physically there are none. It is thus
tenable that perception is susceptible to seemingly random fluctuations in brain activity or …