Background Early-life antibiotic exposure is associated with the development of later obesity
through the disruption of gut microbiota in the animal models. However, the related …

Background In animal studies early life antibiotic exposure causes metabolic abnormalities
including obesity through microbiota disruption, but evidence from human studies is scarce …

Background Prenatal antibiotic exposure has been associated with an altered infant gut
microbiome composition and higher risk of childhood obesity, but no studies have examined …

Antibiotics are often prescribed inappropriately to infants and young children, with potentially
adverse effects on the developing gut microbiota and related metabolic processes. We …

Although abundant evidence has suggested that early-life antibiotic exposure was
associated with adipogenesis later in life, limited data were available on the effect of …

Long-term antibiotic use can have consequences on systemic diseases, such as obesity,
allergy, and depression, implicating the causal role of gut microbiome imbalance. However …

Objective: To investigate whether delivery mode (vaginal versus by caesarean section),
maternal pre-pregnancy body mass index (BMI) and early exposure to antibiotics (< 6 …

We conducted a systematic review and meta‐analysis of observational studies investigating
the association between antibiotic exposure in infancy and risk of childhood overweight and …

Studies in mice suggest that early life represents a critical time window, where antibiotics
may exert profound and lasting effects on the gut microbiota and metabolism. We aimed to …

Purpose Antibiotic use is associated with alteration of the gut microbiome and metabolic
activity. As childhood obesity is a predisposing factor for adult obesity, addressing childhood …