Background Little is known regarding the association between weight change and
accelerated aging. Objectives This study aimed to estimate the influence of weight change …

Background Older adults with discordant biological and chronological ages (BA and CA)
may vary in cognitive and physical function from those with concordant BA and CA. Methods …

Machine learning has been increasingly applied to neuroimaging data to compute
personalized estimates of the biological age of an individual's brain (brain age). The …

Introduction The proportion of older adults within society is sharply increasing and a better
understanding of how we age starts to be critical. However, given the paucity of longitudinal …

Objective Stress and stressful events are associated with poorer health; however, there are
multiple ways to conceptualize and measure stress and stress responses. One physiological …

Objectives The world is witnessing a sharp increase in its elderly population, accelerated by
longer life expectancy and lower birth rates, which in turn imposes enormous medical …

Biological aging is the correlated decline of multi-organ system integrity central to the
etiology of many age-related diseases. A novel epigenetic measure of biological aging …

Aging clocks, built from comprehensive molecular data, have emerged as promising tools in
medicine, forensics, and ecological research. However, few studies have compared the …

Aging is believed to occur across multiple domains, one of which is body composition;
however, attempts to integrate it into biological age (BA) have been limited. Here, we …

Biological aging in people with HIV (PWH) with prolonged successful antiretroviral therapy
(ART) is convoluted and poorly defined. Here, we aimed to investigate the transcriptomics …