[PDF][PDF] Antimicrobial Peptides (AMPs): Potential Therapeutic Strategy against Trypanosomiases? Biomolecules 2023, 13, 599

M Rojas-Pirela, U Kemmerling, W Quinones… - 2023 - academia.edu
Trypanosomiases are a group of tropical diseases that have devastating health and
socioeconomic effects worldwide. In humans, these diseases are caused by the pathogenic …

Antimicrobial peptides (AMPs): potential therapeutic strategy against trypanosomiases?

M Rojas-Pirela, U Kemmerling, W Quiñones… - Biomolecules, 2023 - mdpi.com
Trypanosomiases are a group of tropical diseases that have devastating health and socio-
economic effects worldwide. In humans, these diseases are caused by the pathogenic …

The potential use of natural and structural analogues of antimicrobial peptides in the fight against neglected tropical diseases

A Lewies, JF Wentzel, G Jacobs, LH Du Plessis - Molecules, 2015 - mdpi.com
Recently, research into the development of new antimicrobial agents has been driven by the
increase in resistance to traditional antibiotics and Emerging Infectious Diseases …

Antimicrobial peptides as parasiticidal against human trypanosomatids: mechanisms of action and current status in development

P Mendez-Samperio… - Journal of the Egyptian …, 2013 - journals.ekb.eg
Trypanosomes cause a variety of tropical diseases that affect the livelihood of individuals
worldwide. The currently used pharmaceutical treatments rely on chemotherapy. However …

Nature-derived Peptides as Promising Antiparasitic Agents against Neglected Tropical Diseases

JY Lim, KY Yeong - International Journal of Peptide Research and …, 2024 - Springer
Neglected tropical diseases (NTDs) are a group of at least 20 infectious diseases that
primarily affect tropical regions. Despite impacting 1.6 billion people worldwide, these …

Interactions of antimicrobial peptides with Leishmania and trypanosomes and their functional role in host parasitism

BS McGwire, MM Kulkarni - Experimental parasitology, 2010 - Elsevier
Antimicrobial peptides (AMPs) are multifunctional components of the innate systems of both
insect and mammalian hosts of the pathogenic trypanosomatids Leishmania and …

Antimicrobial peptide action on parasites

M Torrent, D Pulido, L Rivas, D Andreu - Current drug targets, 2012 - ingentaconnect.com
Diseases caused by protozoan parasites can pose a severe thread to human health and are
behind some serious neglected tropical diseases like malaria and leishmaniasis. Though …

Therapeutic potential of antimicrobial peptides against pathogenic protozoa

CL Hagemann, AJ Macedo, T Tasca - Parasitology Research, 2024 - Springer
Protozoal infections cause significant morbidity and mortality in humans and animals. The
use of several antiprotozoal drugs is associated with serious adverse effects and resistance …

Discovery, optimization, and clinical application of natural antimicrobial peptides

AA Rodríguez, A Otero-González, M Ghattas… - Biomedicines, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are widespread in multicellular organisms. These structurally
diverse molecules are produced as the first line of defense against pathogens such as …

[HTML][HTML] Antimicrobial peptides as new-generation antibiotics against Mycobacterium

P Eslami, A Khosravi - Journal of Preventive, Diagnostic and …, 2024 - journals.lww.com
More than 10 million cases of tuberculosis (TB) in 2019 have made TB a global health
problem. The increase in infection has caused an increase in the use of antibiotics for …