UPF-1-UPF-2-UPF-3 complex-orchestrated nonsense-mediated mRNA decay (NMD) is a
well-characterized eukaryotic cellular surveillance mechanism that not only degrades …

Background In addition to acting as an RNA quality control pathway, nonsense-mediated
mRNA decay (NMD) plays roles in regulating normal gene expression. In particular, the …

Nonsense-mediated messenger RNA decay (NMD) represents one of the main surveillance
pathways used by eukaryotic cells to control the quality and abundance of mRNAs and to …

Nonsense-mediated mRNA decay (NMD) is an evolutionarily conserved surveillance
mechanism across eukaryotes and also regulates the expression of physiological …

Recent progress in the technology of transcriptome-wide high-throughput sequencing has
revealed that nonsense-mediated mRNA decay (NMD) targets~ 10% of physiologic …

Nonsense-mediated mRNA decay (NMD) controls the quality of eukaryotic gene expression
and also degrades physiologic mRNAs. How NMD targets are identified is incompletely …

UPF1 is a DNA/RNA helicase with essential roles in nonsense-mediated mRNA decay
(NMD) and embryonic development. How UPF1 regulates target abundance and the …

Nonsense-mediated mRNA decay (NMD) is a highly conserved post-transcriptional gene
regulatory mechanism in eukaryotes (Lykke-Andersen and Jensen, 2015; Kurosaki et al …

Catalase is an important enzyme found in nearly all aerobic organisms and plays an
essential role in protecting cells from oxidative damage by catalyzing the degradation of …

Nonsense-mediated mRNA decay (NMD) is a conserved eukaryotic surveillance pathway
that selectively degrades aberrant mRNAs with premature termination codons (PTCs) …