Despite advances in machine learning-based protein structure prediction, we are still far
from fully understanding how proteins fold into their native conformation. The conventional …

The second volume continues to fill the gap in protein review and protocol literature. It does
this while summarizing recent achievements in the understanding of the relationships …

Proteins are essential elements for life. They are building blocks of all organisms and the
operators of cellular functions. Humans produce a repertoire of at least 30,000 different …

Understanding the second half of the genetic code, ie, protein folding, is not only of immense
importance for using the results of genome sequencing efforts, but also is required to …

This review summarises our current understanding of the underlying and universal
mechanism by which newly synthesised proteins achieve their biologically functional states …

Understanding the mechanisms underlying protein misfolding and aggregation has become
a central issue in biology and medicine. Compelling evidence show that the formation of …

Uncontrolled protein aggregation is a constant challenge in all compartments of living
organisms. The failure of a peptide or protein to remain soluble often results in pathology. So …

Protein misfolding and amyloid assembly have long been recognized as being responsible
for many devastating human diseases. Recent findings indicate that amyloid assemblies …

The aggregation of misfolded proteins is associated with the perturbation of cellular function,
ageing and various human disorders. Mounting evidence suggests that protein aggregation …

Diverse human disorders, including several neurodegenerative diseases and systemic
amyloidosis, are thought to arise from the misfolding and aggregation of an underlying …