Exosome as non-invasive prognostic and diagnostic biomarker and nanovesicle for targeted therapy of non-small cell lung carcinoma

Z Yang, S Fu, Y Li, Y Liang, M Hao, R Guo, C Yu… - Chemical Engineering …, 2023 - Elsevier
Despite enormous evolution in oncopharmacology, the non-small cell lung carcinoma
(NSCLC) is still among the most aggressive and prevalent types of cancer. Late diagnosis …

Exosome-based smart drug delivery tool for cancer theranostics

R Kar, R Dhar, S Mukherjee, S Nag… - ACS biomaterials …, 2023 - ACS Publications
Exosomes are the phospholipid-membrane-bound subpopulation of extracellular vesicles
derived from the plasma membrane. The main activity of exosomes is cellular …

Progress on pivotal role and application of exosome in lung cancer carcinogenesis, diagnosis, therapy and prognosis

MY Li, LZ Liu, M Dong - Molecular cancer, 2021 - Springer
Lung cancer is often diagnosed at an advanced stage and has a poor prognosis.
Conventional treatments are not effective for metastatic lung cancer therapy. Although some …

Improved exosome isolation methods from non-small lung cancer cells (NC1975) and their characterization using morphological and surface protein biomarker …

EO Mahgoub, GM Abdella - Journal of Cancer Research and Clinical …, 2023 - Springer
This study has demonstrated improved methods for isolating exosomes from non-small lung
cancer cells, which address the problems characterized by exosome morphological and …

The role of exosomes in lung cancer metastasis and clinical applications: an updated review

L Yin, X Liu, X Shao, T Feng, J Xu, Q Wang… - Journal of Translational …, 2021 - Springer
Lung cancer is the leading cause of cancer-associated deaths accounting for 24% of all
cancer deaths. As a crucial phase of tumor progression, lung cancer metastasis is linked to …

The roles of tumor-derived exosomes in non-small cell lung cancer and their clinical implications

H Zheng, Y Zhan, S Liu, J Lu, J Luo, J Feng… - Journal of Experimental & …, 2018 - Springer
Non-small cell lung cancer (NSCLC) accounts for approximately 85% of lung cancer cases,
and it is one of the leading causes of cancer death in both men and women worldwide due …

Exosomes in tumor microenvironment: novel transporters and biomarkers

Z Wang, JQ Chen, JL Liu, L Tian - Journal of translational medicine, 2016 - Springer
Tumor microenvironment (TME) plays an integral part in the biology of cancer, participating
in tumor initiation, progression, and response to therapy. Exosome is an important part of …

Advances in exosome research in the management of lung cancer

H Shen, D Cao, X Zhang - Current Topics in Medicinal …, 2023 - ingentaconnect.com
Lung cancer is one of the most common malignant tumors, and its death rate is much higher
than that of colon, kidney, breast, and prostate cancers, and its 5-year survival rate is only …

Formation, contents, functions of exosomes and their potential in lung cancer diagnostics and therapeutics

Z Xia, B Qing, W Wang, L Gu, H Chen… - Thoracic Cancer, 2021 - Wiley Online Library
Lung cancer is the leading cause of cancer‐related death worldwide due to diagnosis in the
advanced stage and drug resistance in the subsequent treatments. Development of novel …

Exosomes: diagnostic biomarkers and therapeutic delivery vehicles for cancer

L Jiang, Y Gu, Y Du, J Liu - Molecular pharmaceutics, 2019 - ACS Publications
Exosomes are described as nanoscale extracellular vesicles (EVs) secreted by multiple cell
types and extensively distributed in various biological fluids. They contain multifarious …