Fluorescent Organic Molecules as Diagnostic and Theranostic Tools for Alzheimer's Disease

K Imran, YA Dhamapurkar, A Sharma - Natural Product-based Synthetic …, 2023 - Springer
Diagnosis of Alzheimer's disease (AD) is crucial especially for the complete comprehension
of pathology and clinical therapy of the disorder, as well as in declining the severity of the …

From Imaging Agents to Theranostic Drugs in Alzheimer's Disease

ML Bolognesi - Comprehensive Medicinal Chemistry III, 2017 - cris.unibo.it
The diagnosis of Alzheimer's disease (AD) took a major step forward in 2012, as Food and
Drug Administration approved the first positron emission tomography tracer. In parallel to …

Recent Advances in Fluorescent Theranostics for Alzheimer's Disease: A Comprehensive Survey on Design, Synthesis, and Properties

TN Francisco, D Malafaia, L Melo, AMS Silva… - ACS …, 2024 - ACS Publications
Alzheimer's disease (AD) is the most common form of neurodegenerative dementia that is
rapidly becoming a major health problem, especially in developed countries because of …

[HTML][HTML] Small-molecule theranostics in Alzheimer's disease

Á Sarabia-Vallejo, P López-Alvarado… - European Journal of …, 2023 - Elsevier
Alzheimer's Disease (AD) remains one of the most challenging health-related issues for our
society. It is becoming increasingly prevalent, especially in developed countries, due to the …

Development of Fluorescent Small Molecules for Imaging of Alzheimer's Disease Biomarkers

C Min, H Ha, J Jeon - Applied Chemistry for Engineering, 2021 - koreascience.kr
Abstract Alzheimer's disease (AD), an irreversible degenerative disorder, is associated with
accumulation and aggregation of amyloid-β peptides, hyperphosphorylated tau proteins …

Biomarkers for Alzheimer's Disease

M Gaddam, ER Motamarri, A Sharma - Natural Product-based Synthetic …, 2023 - Springer
Alzheimer's disease is a neurodegenerative disease, which affects intellectually is frequently
observed in elderly generations and genetically linked individuals. The diagnosis of this …

Frontiers in probing Alzheimer's disease biomarkers with fluorescent small molecules

YW Jun, SW Cho, J Jung, Y Huh, YS Kim… - ACS central …, 2019 - ACS Publications
Alzheimer's disease (AD) is the most common form of dementia. The pathogenesis of the
disease is associated with aggregated amyloid-β, hyperphosphorylated tau, a high level of …

Current strategies for the development of fluorescence-based molecular probes for visualizing the enzymes and proteins associated with Alzheimer's disease

S Ma, G Chen, J Xu, Y Liu, G Li, T Chen, Y Li… - Coordination Chemistry …, 2021 - Elsevier
One of the most prevalent forms of dementia is Alzheimer's disease (AD) which causes
severe memory impairment within humans. As such, research into the early diagnosis of AD …

Small molecular fluorescent probes for Alzheimer's disease associated active species

F Tang, K Wang, X Liu, X Zhang, W Zhou… - … A European Journal, 2023 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and is the main
cause of dementia worldwide. As the pathogenesis of AD is quite complicated, there is …

From companion diagnostics to theranostics: a new avenue for alzheimer's disease? Miniperspective

ML Bolognesi, A Gandini, F Prati… - Journal of Medicinal …, 2016 - ACS Publications
The recent literature signals a growing paradigm shift toward integrating therapeutics and
diagnostics rather than developing and deploying them separately. In this gradual move …