Associations of atrial natriuretic peptide with measures of insulin and adipose depots

CA Couch, LA Fowler, V Parcha, P Arora… - Physiological …, 2023 - Wiley Online Library
Low concentrations of natriuretic peptides (NPs) have been associated with greater risk for
Type 2 diabetes (T2D). African American individuals (AA) have lower NP levels and are …

Serum proatrial natriuretic peptide concentrations during oral glucose-induced acute hyperinsulinemia in lean and obese men

CL Asferg, SJ Nielsen, UB Andersen, A Linneberg… - Peptides, 2019 - Elsevier
Atrial natriuretic peptide (ANP) is primarily seen as a hormone involved in salt and water
homeostasis and blood pressure regulation. Evidence supports a link between metabolism …

Atrial natriuretic peptide in the high normal range is associated with lower prevalence of insulin resistance

A Jujić, PM Nilsson, M Persson, JJ Holst… - The Journal of …, 2016 - academic.oup.com
Context: We have previously shown that high levels of atrial natriuretic peptides (ANPs) are
associated with decreased risk of future diabetes development; however, the mechanism …

Expression and secretion of the atrial natriuretic peptide in human adipose tissue and preadipocytes

G Garruti, V Giusti, J Nussberger, C Darimont… - …, 2007 - Wiley Online Library
Objective: Atrial natriuretic peptide (ANP) is a secretory hormone displaying diuretic,
natriuretic, and vasorelaxant activities. Recently, its lipolytic activity has been reported. Since …

Differential response of the natriuretic peptide system to weight loss and exercise in overweight or obese patients

S Haufe, J Kaminski, W Utz, V Haas… - Journal of …, 2015 - journals.lww.com
Objective: Relative atrial natriuretic peptide (ANP) deficiency has been implicated in the
pathogenesis of obesity-associated cardiovascular and metabolic disease. We tested the …

Acute effects of insulin on circulating natriuretic peptide levels in humans

KN Bachmann, SM Deger, A Alsouqi, S Huang, M Xu… - PLoS …, 2018 - journals.plos.org
Background The natriuretic peptide hormones play an important role in salt and blood
pressure regulation. In observational studies, obesity and insulin resistance have been …

Higher natriuretic peptide levels associate with a favorable adipose tissue distribution profile

IJ Neeland, BR Winders, CR Ayers, SR Das… - Journal of the American …, 2013 - jacc.org
Objectives: The goal of this study was to investigate the association between natriuretic
peptides and body fat distribution in a multiethnic cohort. Background: Natriuretic peptides …

Metabolic rather than body composition measurements are associated with lower serum natriuretic peptide concentrations in normal weight and obese men

CL Asferg, SJ Nielsen, UB Andersen… - American journal of …, 2014 - academic.oup.com
BACKGROUND Several studies have shown that obese persons have lower circulating
natriuretic peptide (NP) concentrations. The cause of the relative NP deficiency seen in …

Relation of visceral adiposity to circulating natriuretic peptides in ambulatory individuals

S Cheng, CS Fox, MG Larson, JM Massaro… - The American journal of …, 2011 - Elsevier
Natriuretic peptides have important roles in the regulation of vasomotor tone, salt
homeostasis, and ventricular remodeling. Lower natriuretic peptide levels observed in …

Association of plasma natriuretic peptide levels with metabolic risk factors in ambulatory individuals

TJ Wang, MG Larson, MJ Keyes, D Levy, EJ Benjamin… - Circulation, 2007 - Am Heart Assoc
Background—Experimental studies suggest that the natriuretic peptides influence lipid and
fatty acid metabolism. Although it has been shown that obese individuals have reduced …