In vitro Analytical Techniques as Screening Tools to investigate the Metal chelate‐DNA interactions

N Varghese, JR Jose, PM Krishna, D Philip… - …, 2023 - Wiley Online Library
Deoxyribose nucleic acid (DNA) is found to be the most efficient pharmacological target of
many synthetic molecules which are deemed as potential drugs with clinical applications …

[HTML][HTML] Drug–DNA interactions and their study by UV–Visible, fluorescence spectroscopies and cyclic voltametry

M Sirajuddin, S Ali, A Badshah - Journal of Photochemistry and …, 2013 - Elsevier
The present paper review the drug–DNA interactions, their types and applications of
experimental techniques used to study interactions between DNA and small ligand …

[PDF][PDF] Experimental techniques employed in the study of metal complexes-DNA–interactions

T Topală, A Bodoki, L Oprean, R Oprean - Exp. Tech, 2014 - farmaciajournal.com
The present paper is an overlook on metal complexes-DNA interactions, their classification
and the experimental techniques employed to study them. The deoxyribonucleic acid (DNA) …

Computational and experimental binding mechanism of DNA-drug interactions

C Selvaraj, SK Singh - Current Pharmaceutical Design, 2018 - ingentaconnect.com
Nucleic acid is the key unit and a predominant genetic material for interpreting the
fundamental basis of genetic information in an organism and now it is used for the evolution …

Investigations of drug–DNA interactions using molecular docking, cyclic voltammetry and UV–Vis spectroscopy

F Perveen, R Qureshi, FL Ansari, S Kalsoom… - Journal of Molecular …, 2011 - Elsevier
Molecular docking and QSAR studies were carried out for the investigation of interactions
between 11 antitumor drugs and double stranded DNA. Quantitative structure activity …

Multi-spectroscopic and electrochemical approaches of the interaction between a new binuclear agent and DNA

M Saeidifar, Z Sohrabi Jam, S Shahraki… - Journal of …, 2017 - Taylor & Francis
Metal complexes have been widely applied in the field of medicine for centuries, yet their
molecular mechanisms are not fully understood. It is well known that metal ions present in …

[HTML][HTML] Anticancer drugs' deoxyribonucleic acid (DNA) interactions

SH Alotaibi, AA Momen - Biophysical chemistry-advance …, 2019 - intechopen.com
The deoxyribonucleic acid (DNA) is the molecule of life that controls all the chemical
changes that take place in cells. The interaction of drugs with DNA is among the most …

Cyclic voltammetric DNA binding investigations on some anticancer potential metal complexes: a review

N Arshad, SI Farooqi - Applied biochemistry and biotechnology, 2018 - Springer
Cancer is developed by rapid, uncontrolled, and abnormal cell proliferation and one of the
leading causes of deaths worldwide in human beings. For the remedial measures of …

Non-covalent binding studies of transition metal complexes with DNA: A review

N Kumar, R Kaushal, P Awasthi - Journal of Molecular Structure, 2023 - Elsevier
Transition metal complexes are widely used therapeutic agents due to their small size,
various coordination numbers, geometries, physiologically relevant redox potentials, as well …

Cyclic voltammetry-an electrochemical approach to study metal-based potential antitumor drug-DNA interaction

F Arjmand, M Aziz, S Tabassum - Current Analytical Chemistry, 2011 - ingentaconnect.com
The application of electrochemical measurements of the redox couples of metal-based
antitumor potential drugs in the presence of DNA is a highly sensitive method due to the …