Pulmonary multidrug codelivery of curcumin nanosuspensions and ciprofloxacin with N-acetylcysteine for lung infection therapy

Y Liu, Y Ma, L Xue, W Guan, Y Wang - Journal of Drug Delivery Science …, 2023 - Elsevier
To better address the etiology of lung infections and the delivery limitations that exist, the
development of a pulmonary inhalation formulation with antibacterial and mucolytic effects is …

Pulmonary delivery of curcumin and beclomethasone dipropionate in a multicomponent nanosuspension for the treatment of bronchial asthma

L Casula, F Lai, E Pini, D Valenti, C Sinico, MC Cardia… - Pharmaceutics, 2021 - mdpi.com
Curcumin has shown a potential extraordinary activity as an add-on ingredient in asthma
treatment, due to its immunomodulatory and anti-inflammatory mechanism of action …

Controlled release pulmonary administration of curcumin using swellable biocompatible microparticles

IM El-Sherbiny, HDC Smyth - Molecular pharmaceutics, 2012 - ACS Publications
This study involves a promising approach to achieve sustained pulmonary drug delivery. Dry
powder particulate carriers were engineered to allow simultaneous aerosol lung delivery …

Ciprofloxacin nanocrystals and N-acetylcysteine co-solidified powders for pulmonary drug delivery: development and in vitro and in vivo characterization

W Guan, Y Liu, S Ding, Y Wang - Journal of Nanoparticle Research, 2022 - Springer
This study evaluated the feasibility of ciprofloxacin nanocrystals dry powder inhalations
(DPIs) co-delivered with N-acetylcysteine (NAC) to improve the drug permeability and …

Evaluation of High-Performance Curcumin Nanocrystals for Pulmonary Drug Delivery Both In Vitro and In Vivo

L Hu, D Kong, Q Hu, N Gao, S Pang - Nanoscale research letters, 2015 - Springer
This paper focused on formulating high-performance curcumin spray-dried powders for
inhalation (curcumin-DPIs) to achieve a high lung concentration. Curcumin-DPIs were …

Pulmonary delivery of curcumin and quercetin nanoparticles for lung cancer–Part 1: aerosol performance characterization

CY Loo, D Traini, PM Young, T Parumasivam… - Journal of Drug Delivery …, 2023 - Elsevier
Pulmonary delivery could be an effective method to provide higher dose of
chemotherapeutic drugs onto the lung as well as minimize systemic toxicity. In this study …

[Retracted] A Novel Curcumin‐Based Drug Powder Inhalation Medicine for Chronic Obstructive Pulmonary Disease

Q Shen, Y Jiang, J Chen, X Wang… - Bioinorganic Chemistry …, 2021 - Wiley Online Library
The dry powder inhaler is a new form of drug delivery that is widely used as an alternative to
traditional drug delivery methods, addressing the shortcomings of traditional drug delivery …

Fabrication of nanocomposite particles using a two-solution mixing-type spray nozzle for use in an inhaled curcumin formulation

M Taki, T Tagami, K Fukushige, T Ozeki - International journal of …, 2016 - Elsevier
A unique two-solution mixing-type spray nozzle is useful for producing nanocomposite
particles (microparticles containing drug nanoparticles) in one step. The nanocomposite …

Dry powder aerosols of curcumin-chitosan nanoparticle complex prepared by spray freeze drying and their antimicrobial efficacy against common respiratory bacterial …

H Yu, TT Tran, J Teo, K Hadinoto - Colloids and Surfaces A …, 2016 - Elsevier
While the therapeutic benefits of curcumin delivery to the lung to treat various pulmonary
disorders have been established, development of inhaled curcumin formulation that can …

Curcumin acetate nanocrystals for sustained pulmonary delivery: preparation, characterization and in vivo evaluation

X Hu, FF Yang, XL Wei, GY Yao, CY Liu… - Journal of …, 2017 - ingentaconnect.com
The main objective of this study was to test the hypothesis that inhaled nanocrystals of a
highly lipophilic drug could be used as a novel approach for producing sustained pulmonary …