Abstract Poly (ADP‐ribosyl) ation (PARylation) is an important post‐translational
modification of proteins that involves the transfer of ADP‐ribose moieties, and plays …

Background During fertilization, pronuclear envelope breakdown (PNEB) is followed by the
mingling of male and female genomes. Dynamic chromatin and protein rearrangements …

Besides the established central role of poly (ADP-ribose) polymerase-1 (Parp-1) and Parp-2
in the maintenance of genomic integrity, accumulating evidence indicates that poly (ADP …

Somatic cell nuclear transfer is an important technique for life science research, but its
efficiency is still extremely low, and most genes that are important during early development …

Abstract Poly (ADP-ribosyl) ation (PARylation) plays important roles in DNA repair,
apoptosis, transcriptional regulation, and cell death, and occurs via the activity of poly (ADP …

ABSTRACT PLD1 has been implicated in cytoskeletal reorganization and vesicle trafficking
in somatic cells; however, its function remains unclear in oocyte meiosis. Herein, we found …

Before fertilization, mammalian oocyte undergoes an asymmetric division which depends on
eccentric positioning of the spindle at the oocyte cortex to form a polar body and an egg …

PARP family members can be found spread across all domains and continue to be essential
molecules from lower to higher eukaryotes. Poly (ADP‐ribose) polymerase 1 (PARP‐1) …

Protein regulator of cytokinesis 1 (PRC1) is a microtubule bundling protein that is involved in
the regulation of the central spindle bundle and spindle orientation during mitosis. However …

In spermiogenesis, spermatid differentiation is marked by dramatic changes in chromatin
density and composition. The extreme condensation of the spermatid nucleus is …