Caloric restriction induced epigenetic effects on aging

J Zhai, WH Kongsberg, Y Pan, C Hao… - Frontiers in Cell and …, 2023 - frontiersin.org
Aging is the subject of many studies, facilitating the discovery of many interventions.
Epigenetic influences numerous life processes by regulating gene expression and also …

Epigenetic regulation of caloric restriction in aging

Y Li, M Daniel, TO Tollefsbol - BMC medicine, 2011 - Springer
The molecular mechanisms of aging are the subject of much research and have facilitated
potential interventions to delay aging and aging-related degenerative diseases in humans …

The impact of caloric restriction on the epigenetic signatures of aging

N Gensous, C Franceschi, A Santoro… - International journal of …, 2019 - mdpi.com
Aging is characterized by an extensive remodeling of epigenetic patterns, which has been
implicated in the physiopathology of age-related diseases. Nutrition plays a significant role …

How calorie restriction slows aging: an epigenetic perspective

GM Lim, N Maharajan, GW Cho - Journal of Molecular Medicine, 2024 - Springer
Genomic instability and epigenetic alterations are some of the prominent factors affecting
aging. Age-related heterochromatin loss and decreased whole-genome DNA methylation …

Stem cell rejuvenation and the role of autophagy in age retardation by caloric restriction: An update

S Bi, H Wang, W Kuang - Mechanisms of Ageing and Development, 2018 - Elsevier
Stem cells being pluripotent in nature can differentiate into a wide array of specific cells and
asymmetrically divide to produce new ones but may undergo aging by themselves. Aging …

Effects of caloric restriction on the antagonistic and integrative hallmarks of aging

B Erbaba, A Arslan-Ergul, MM Adams - Ageing Research Reviews, 2021 - Elsevier
Aging is a significant risk factor for cognitive decline associated with neurodegenerative
diseases, which makes understanding what promotes 'healthy brain aging'very important …

Towards an understanding of the anti-aging mechanism of caloric restriction

G Cavallini, A Donati, Z Gori… - Current aging science, 2008 - ingentaconnect.com
Accumulation of oxidatively altered cell components may play a role in the age-related cell
deterioration and associated diseases. Caloric restriction is the most robust anti-aging …

Epigenetic Modifiers as Game Changers for Healthy Aging

S Sharma, R Bhonde - Rejuvenation Research, 2023 - liebertpub.com
Epigenetic alterations during aging are manifested with altered gene expression linking it to
lifespan regulation, genetic instability, and diseases. Diet and epigenetic modifiers exert a …

The effects of graded caloric restriction: XII. Comparison of mouse to human impact on cellular senescence in the colon

L Fontana, SE Mitchell, B Wang, V Tosti, T van Vliet… - Aging …, 2018 - Wiley Online Library
Calorie restriction (CR) is an effective strategy to delay the onset and progression of aging
phenotypes in a variety of organisms. Several molecular players are involved in the anti …

The effects of calorie restriction on autophagy: role on aging intervention

KW Chung, HY Chung - Nutrients, 2019 - mdpi.com
Autophagy is an important housekeeping process that maintains a proper cellular
homeostasis under normal physiologic and/or pathologic conditions. It is responsible for the …