[图书][B] A Novel Mouse Model for the Study of Spinal Cord Injuryassociated Heterotopic Ossification

R Aita - 2023 - search.proquest.com
Background: About 900,000 individuals suffer a traumatic spinal cord injury (SCI) every year.
SCI severely impacts the quality of life and increases the risk for debilitating sequelae. One …

[PDF][PDF] A novel mouse model of polytrauma with spinal cord injury–associated heterotopic ossification

R Aita, G Unnithan, T Klaylat, JA Petruccelli… - European Cells and …, 2024 - ecmjournal.org
Heterotopic ossification (HO) refers to abnormal bone formation in soft tissues, which is a
common complication of traumatic spinal cord injury (SCI). Current therapeutic approaches …

9. Novel murine model of heterotopic ossification induced by spinal cord injury

R Aita, J Petruccelli, R Gawri, C Gao - The Spine Journal, 2022 - Elsevier
BACKGROUND CONTEXT Heterotopic ossification (HO) is a painful and debilitating
condition causing abnormal bone formation in the soft tissues reported in up to 50% of …

[PDF][PDF] Novel mouse model of spinal cord injury-induced heterotopic ossification.

H Kang, ABC Dang, SK Joshi, B Halloran… - Journal of …, 2014 - researchgate.net
Heterotopic ossification (HO) develops in about 20% to 30% of patients with spinal cord
injury (SCI) and significantly impairs their rehabilitation. There is no effective prevention or …

Neurological heterotopic ossification following spinal cord injury is triggered by macrophage‐mediated inflammation in muscle

F Genêt, I Kulina, C Vaquette, F Torossian… - The Journal of …, 2015 - Wiley Online Library
Neurological heterotopic ossification (NHO) is the abnormal formation of bone in soft tissues
as a consequence of spinal cord or traumatic brain injury. NHO causes pain, ankyloses …

Interleukin‐1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification

HW Tseng, I Kulina, D Girard, J Gueguen… - Journal of Bone and …, 2020 - academic.oup.com
Neurogenic heterotopic ossifications (NHOs) form in periarticular muscles after severe
spinal cord (SCI) and traumatic brain injuries. The pathogenesis of NHO is poorly …

Peripheral denervation participates in heterotopic ossification in a spinal cord injury model

C Debaud, M Salga, L Begot, X Holy, M Chedik… - PloS one, 2017 - journals.plos.org
We previously reported the development of a new acquired neurogenic HO (NHO) mouse
model, combining spinal cord transection (SCI) and chemical muscle injury. Pathological …

[HTML][HTML] MRM Insights: A Mouse Model for Studying Neurogenic Heterotopic Ossification in Spinal Cord Injury

MRM Talks - mrm.research.mcgill.ca
Every month, in the MRM Insights, a member of the MRM Network offers a unique
perspective on the topics of stem cells and regenerative medicine. In this edition, Dr. Chan …

[PDF][PDF] Heterotopic Ossification Following Spinal Cord Injury

F Alibrahim - scireproject.com
Heterotopic ossification (HO) is the formation of pathological bone in muscle or soft tissue
(Shehab, Elgazzar & Collier, 2018). The incidence in individuals following a spinal cord …

Development of an animal model for traumatic brain injury augmentation of heterotopic ossification in response to local injury

C Kesavan, GA Gomez, S Pourteymoor, S Mohan - Biomedicines, 2023 - mdpi.com
Heterotopic ossification (HO) is the abnormal growth of bone in soft connective tissues that
occurs as a frequent complication in individuals with traumatic brain injury (TBI) and in rare …