Intranasal inorganic cerium oxide nanoparticles ameliorate oxidative stress induced motor manifestations in haloperidol-induced parkinsonism

Mohammad, UA Khan, Z Saifi, J Bora, MH Warsi… - …, 2023 - Springer
Cerium oxide nanoparticles (CONPs), owing to their radical scavenging property, have
recently emerged as a therapeutic candidate for oxidative stress-mediated neurological …

Intranasal cerium oxide nanoparticles improves locomotor activity and reduces oxidative stress and neuroinflammation in haloperidol-induced parkinsonism in rats

Mohammad, UA Khan, MH Warsi… - Frontiers in …, 2023 - frontiersin.org
Introduction: Cerium oxide nanoparticles (CONPs) have been investigated for their
therapeutic potential in Parkinson's disease (PD) due to their potent and regenerative …

Intranasal cerium oxide nanoparticles ameliorate cognitive function in rats with Alzheimer's via anti-oxidative pathway

SM Danish, A Gupta, UA Khan, N Hasan, FJ Ahmad… - Pharmaceutics, 2022 - mdpi.com
Cerium oxide nanoparticles (CNPs), owing to their antioxidant property, have recently
emerged as therapeutic candidate for Alzheimer's disease (AD). However, intravenous …

[PDF][PDF] Intranasal cerium oxide nanoparticles ameliorate cognitive function in rats with alzheimer's via anti-oxidative pathway. Pharm. 2022; 14 (4): 756

SM Danish, A Gupta, UA Khan, N Hasan, FJ Ahmad… - 2022 - academia.edu
Cerium oxide nanoparticles (CNPs), owing to their antioxidant property, have recently
emerged as therapeutic candidate for Alzheimer's disease (AD). However, intravenous …

Vitamin E Loaded Naringenin Nanoemulsion via Intranasal Delivery for the Management of Oxidative Stress in a 6‐OHDA Parkinson's Disease Model

B Gaba, T Khan, MF Haider, T Alam… - BioMed research …, 2019 - Wiley Online Library
Purpose. The present study is an attempt to develop a vitamin E loaded naringenin (NRG)
Nanoemulsion (NE) for direct nose‐to‐brain delivery for better management of Parkinson …

Amelioration of oxidative stress utilizing nanoemulsion loaded with bromocriptine and glutathione for the management of Parkinson's disease

MU Ashhar, P Vyas, D Vohora, PK Sahoo… - International Journal of …, 2022 - Elsevier
Parkinson's disease (PD) is triggered by the formation of free radicals in dopaminergic
neurons, which results in oxidative stress-induced neurodegeneration. The objective of the …

[HTML][HTML] Intranasal administration of edaravone nanoparticles improves its stability and brain bioavailability

Y Lu, JTW Wang, N Li, X Zhu, Y Li, S Bansal… - Journal of Controlled …, 2023 - Elsevier
The clinical application of EDV, a potent antioxidant drug approved for amyotrophic lateral
sclerosis (ALS), is limited by its short biological half-life and poor water solubility …

Cerium oxide nanoparticles: a 'radical'approach to neurodegenerative disease treatment

S Naz, J Beach, B Heckert, T Tummala… - …, 2017 - Taylor & Francis
Despite advances in understanding the factors that cause many neurodegenerative
diseases (NDs), no current therapies have yielded significant results. Cerium oxide …

Selegiline nanoformulation in attenuation of oxidative stress and upregulation of dopamine in the brain for the treatment of Parkinson's disease

S Kumar, S Dang, K Nigam, J Ali… - Rejuvenation research, 2018 - liebertpub.com
Objective of this study was to determine whether the prepared nanoemulsion would be able
to deliver selegiline to the brain by intranasal route, improving its bioavailability. Antioxidant …

Stimuli-responsive nanoparticles delivered by a nasal-brain pathway alleviate depression-like behavior through extensively scavenging ROS

L Liu, M Liu, J Xiu, B Zhang, H Hu, M Qiao, D Chen… - Acta Biomaterialia, 2023 - Elsevier
Depression is one of the most common mental diseases, which seriously affects patients'
physical and mental health. Emerging evidence has indicated that oxidative stress (OS) is a …