The associations of socioeconomic status with incident dementia and Alzheimer's disease are modified by leucocyte telomere length: A population-based cohort study

KY Lai, C Webster, S Kumari, JEJ Gallacher… - Scientific reports, 2023 - nature.com
Socio-economic status (SES) and biological aging are risk factors for dementia, including
Alzheimer's disease, however, it is less clear if the associations with SES vary sufficiently …

Short leukocyte telomeres predict 25-year Alzheimer's disease incidence in non-APOE ε4-carriers

FS Hackenhaar, M Josefsson, AN Adolfsson… - Alzheimer's research & …, 2021 - Springer
Background Leukocyte telomere length (LTL) has been shown to predict Alzheimer's
disease (AD), albeit inconsistently. Failing to account for the competing risks between AD …

Exploring the causal pathway from telomere length to Alzheimer's disease: an update Mendelian randomization study

K Gao, C Wei, J Zhu, X Wang, G Chen, Y Luo… - Frontiers in …, 2019 - frontiersin.org
Increasing evidence shows that telomere length shortening is associated with the risk for
Alzheimer's disease (AD), pointing to a potential modifiable target for prevention. However …

Telomere length and the risk of Alzheimer's disease: the Rotterdam study

L Fani, S Hilal, S Sedaghat, L Broer… - Journal of …, 2020 - content.iospress.com
There is a wide interest in biomarkers that capture the burden of detrimental factors as these
accumulate with the passage of time, ie, increasing age. Telomere length has received …

Leukocyte telomere length shortening and Alzheimer's disease etiology

Y Guo, H Yu - Journal of Alzheimer's Disease, 2019 - content.iospress.com
Background: Several observational studies have found leukocyte telomere length (TL) to be
associated with Alzheimer's diseases (AD) or dementia. However, these findings were …

Associations of socioeconomic status and healthy lifestyle with incident early-onset and late-onset dementia: a prospective cohort study

R Li, R Li, J Xie, J Chen, S Liu, A Pan… - The Lancet Healthy …, 2023 - thelancet.com
Background Modifiable risk factor estimates are sparse for early-onset dementia incidence.
This study aimed to estimate and compare the risk factor profiles of early-onset dementia …

Association between individual-level socioeconomic position and incident dementia using UK Biobank data: a prospective study

KY Lai, C Webster, S Kumari, JEJ Gallacher, C Sarkar - The Lancet, 2022 - thelancet.com
Background Under-education and living in poverty are known risk factors for dementia.
However, single-variable makers of socioeconomic position (SEP) are often correlated and …

Which risk factors causally influence dementia? A systematic review of Mendelian randomization studies

E Kuźma, E Hannon, A Zhou, I Lourida… - Journal of …, 2018 - content.iospress.com
Background: Numerous risk factors for dementia are well established, though the causal
nature of these associations remains unclear. Objective: To systematically review Mendelian …

[HTML][HTML] Leucocyte telomere length, brain volume and risk of dementia: a prospective cohort study

Z Cao, Y Hou, C Xu - General Psychiatry, 2023 - ncbi.nlm.nih.gov
Background The evidence regarding the association between leucocyte telomere length
(LTL) and brain health is sparse and inconclusive. Aims To investigate the associations of …

Genetically predicted telomere length and Alzheimer's disease endophenotypes: a Mendelian randomization study

B Rodríguez-Fernández, N Vilor-Tejedor… - Alzheimer's research & …, 2022 - Springer
Telomere length (TL) is associated with biological aging, consequently influencing the risk of
age-related diseases such as Alzheimer's disease (AD). We aimed to evaluate the potential …