Germanium dioxide nanoparticles mitigate biochemical and molecular changes characterizing Alzheimer's disease in rats

SA Abdel Gaber, AH Hamza, MA Tantawy, EA Toraih… - Pharmaceutics, 2023 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder that jeopardizes the lives of
diagnosed patients at late stages. This study aimed to assess, for the first time, the efficiency …

Geniposide and Harpagoside Functionalized Cerium Oxide Nanoparticles as a Potential Neuroprotective

RM Pérez Gutiérrez, LM Rodríguez-Serrano… - International Journal of …, 2024 - mdpi.com
Alzheimer's disease is associated with protein aggregation, oxidative stress, and the role of
acetylcholinesterase in the pathology of the disease. Previous investigations have …

The effect of cerium dioxide nanoparticles on the viability of hippocampal neurons in Alzheimer's disease modeling

VV Hanzha, NM Rozumna, YV Kravenska… - Frontiers in Cellular …, 2023 - frontiersin.org
The possibilities of using nanoparticle materials based on cerium dioxide (CNPs) are
exciting since they are low toxic and have specific redox, antiradical properties. It can be …

Nanoparticles as potential clinical therapeutic agents in Alzheimer's disease: focus on selenium nanoparticles

M Nazıroğlu, S Muhamad, L Pecze - Expert review of clinical …, 2017 - Taylor & Francis
ABSTRACT Introduction: In etiology of Alzheimer's disease (AD), involvement of amyloid β
(Aβ) plaque accumulation and oxidative stress in the brain have important roles. Several …

Gold nanoparticles prevent cognitive deficits, oxidative stress and inflammation in a rat model of sporadic dementia of Alzheimer's type

AP Muller, GK Ferreira, AJ Pires… - Materials Science and …, 2017 - Elsevier
Alzheimer's disease (AD) is the most common form of neurodegenerative dementia in the
aged brain. Even though its etiology is unknown, factors such as neuroinflammation …

Cerium oxide nanoparticles trigger neuronal survival in a human Alzheimer disease model by modulating BDNF pathway

B D'Angelo, S Santucci, E Benedetti… - Current …, 2009 - ingentaconnect.com
In engineering and materials science, nanotechnology has made significant advances in the
reduction of free radical damage. Despite such advances, there has been little application to …

Anti-Alzheimer, antioxidants, glucose-6-phosphate dehydrogenase effects of Taverniera glabra mediated ZnO and Fe2O3 nanoparticles in alloxan-induced diabetic …

AU Khan, M Mohany, HU Khan, F Fozia, S Khan… - Open …, 2023 - degruyter.com
The current study aimed to assess the neuroprotective effect of Zn and Fe oxide
nanoparticles biofabricated by Taverniera glabra in alloxan-induced diabetic rats. The …

Safety Evaluation of Cerium Oxide Nanoparticles Using Wild Type and Transgenic Drosophila Melanogaster Model of Alzheimers Disease

S Vignesh - shodhganga.inflibnet.ac.in
Alzheimer s disease (AD) is a neurodegenerative disorder that causes progressive
deterioration of memory, cognitive skills, locomotor functions, and quality of life. AD is a …

Functionalized Cerium Dioxide Nanoparticles with Antioxidative Neuroprotection for Alzheimer's Disease

Y Hu, H Guo, S Cheng, J Sun, J Du, X Liu… - International Journal …, 2023 - Taylor & Francis
Background Oxidative stress induced reactive oxygen species (ROS) and aggregation of
amyloid β (Aβ) in the nervous system are significant contributors to Alzheimer's disease …

[HTML][HTML] Graphene oxide improves postoperative cognitive dysfunction by maximally alleviating amyloid beta burden in mice

J Zhang, S Zhu, P Jin, Y Huang, Q Dai, Q Zhu, P Wei… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Graphene oxide (GO) based nanomaterials have shown potential for the
diagnosis and treatment of amyloid-β (Aβ)-related diseases, mainly on Alzheimer's disease …