Increasingly extreme weather events in high malaria burden areas threaten progress to
disease control targets. Yet, data on the impact of these events on control programs remain …

A series of novel immunoadjuvant QS-21 analogs were synthesized, and their effects on the
in vitro hemolysis of red blood cells were evaluated using QS-21 as a control and hemolytic …

疟疾是一种危害严重的全球性传染疾病, 曾在我国严重肆虐. 近年来全球疟疾防控形势停滞不前,
我国也面临巨大输入性疟疾威胁, 亟需有效的疟疾疫苗作为现有防控措施之外的新增手段 …

After several decades in development, two malaria vaccines based on the same antigen and
with very similar constructs and adjuvants, RTS, S/AS01 (RTS, S) and R21/Matrix-M (R21) …

The Walter Reed Project is a collaboration between the Walter Reed Army Institute of
Research of the United States Department of Defense and the Kenya Medical Research …

Knowing whether vaccine protection wanes over time is important for health policy and drug
development. However, quantifying waning effects is difficult. A simple contrast of vaccine …

The generation of an anti-malarial vaccine that produces broad, potent, and durable
responses is highly desirable to control the burden of Plasmodium falciparum disease …

Background The RTS, S/AS01E vaccine has been authorized for use in children in sub-
Saharan Africa from the age of 5 months. Nevertheless, there is a limited number of clinical …

mRNA vaccines have become a central part of vaccine research over the last decade due to
their application in cancer immunotherapy, and more recently, the rapid response to the …

Plasmodium falciparum malaria, a mosquito-borne, unicellular parasitic disease, remains a
major health concern, particularly in the sub-Saharan Africa. Despite many attempts to …