Investigating Therapeutic Efficacy of Dacarbazine and Temozolomide, Alone and in Combination with BRAF (V600E) siRNA in A375 Human Melanoma Cell Line

F Tabandeh, RM Tehrani, M Sharifi, E Toopchi - 2024 - researchsquare.com
Melanoma is one of the variable nature and deadliest form of skin cancers and the mutations
play a major role in its development. It has faced many challenges in treatment and has led …

[PDF][PDF] The role of osteopontin expression during malignant melanoma progression

T Kiss - 2024 - dea.lib.unideb.hu
Melanoma is one of the most malignant forms of cancers and represents a significant public
health problem globally, with several histopathological subtypes and varying incidence rates …

RNAi-Based Therapy: Prospect as Cancer Treatment

SE Soentoro, M Timothy, J Jo - Medicinus, 2024 - ojs.uph.edu
Cancer is one of the deadliest form of diseases in humans, with the annual deaths ranging
in the millions. Conventional treatments including chemotherapy, radiotherapy, or surgery …

Studies on the regulation of the activity potential of Matrix Metalloproteinase 2

HZ Sarker - 2024 - era.library.ualberta.ca
Abstract Matrix metalloproteinase 2 (MMP2), also known as gelatinase A or 72 kDa type IV
collagenase, is a member of a family of 25 different Zn2+-dependent endopeptidases that …

Étude du rôle des micro-ARN cellulaires au cours de l'infection par le VIH-1

N Bellini - 2024 - papyrus.bib.umontreal.ca
Avec plus de 39 millions de personnes infectées à travers le monde, le virus de
l'immunodéficience humaine de type-1 (VIH-1) est un problème majeur de santé publique …

Modern gene therapy drugs

EV Galitsyna, EA Kulikova, IA Paveliev… - Genes & Cells, 2024 - genescells.ru
Gene therapy is a modern and effective approach for treating diseases previously
considered incurable by traditional methods. Its main strategy is to transfer the genetic …

Characterization of serum extracellular vesicles and their differential level of miR-197-3p in familial Mediterranean fever patients

Z Tavukcuoglu, YZ Akkaya-Ulum, N Yersal… - … Nucleotides & Nucleic …, 2024 - Taylor & Francis
Objectives The aim of this study was to analyze the existence of miRNAs derived from serum
extracellular vesicles (EVs) in familial Mediterranean fever (FMF) patients. Our group has …

[图书][B] Enhancing the efficiency of viral and non-viral gene delivery vectors

S Bazaz - 2024 - openarchive.ki.se
Gene therapy, which involves the introduction, alteration, or deletion of genetic material
within cells to treat or prevent disease, holds great promise for addressing various genetic …

RNA não codificantes e cancro

ARC Almeida - 2024 - comum.rcaap.pt
Cancro é o termo utilizado para denominar um vasto conjunto de doenças que provocam
alterações nas células e podem reduzir consideravelmente a qualidade e esperança de …

Peran RNAi dalam Menghambat Pertumbuhan Kanker: Meninjau Efek Knockdown pada Ekspresi Gen

L Yunaini, DA Suryandari, P Sari - Pratista Patologi, 2024 - majalahpratistapatologi.com
RNAi memiliki peranan penting dalam menahan laju perkembangan kanker dengan focus
pada efek knockdown terhadap ekspresi gen. Analisis literatur baru dilakukan untuk …