In mice, periodic cycles of a fasting mimicking diet (FMD) protect normal cells while killing
damaged cells including cancer and autoimmune cells, reduce inflammation, promote multi …

The associations of polycyclic aromatic hydrocarbons (PAHs) with cardiovascular diseases
(CVDs) and all-cause mortality are unclear, especially the joint effects of PAHs exposure …

Organismal aging is inherently connected to the aging of its constituent cells and systems.
Reducing the biological age of the organism may be assisted by reducing the age of its cells …

Chronic musculoskeletal pain is often associated with lower socioeconomic status (SES).
SES correlates with psychological and environmental conditions that could contribute to the …

Motivation Aging is intricately linked to diseases and mortality. It is reflected in molecular
changes across various tissues which can be leveraged for the development of biomarkers …

Complicated associations between multiplexed environmental factors and aging are poorly
understood. We manipulated aging using multidimensional metrics such as phenotypic age …

To test the hypothesis that early-life adversity accelerates the pace of biological aging, we
analyzed data from the Dutch Hunger Winter Families Study (DHWFS, N= 951). DHWFS is a …

Nicotinamide riboside (NR) increases blood levels of NAD+, a cofactor central to energy
metabolism, and improves brain function in some rodent models of neurodegeneration. We …

Ageing is often characterised by progressive accumulation of damage, and it is one of the
most important risk factors for chronic disease development. Epigenetic mechanisms …

Age remains the central risk factor for many neurodegenerative diseases including
Parkinson's disease, Alzheimer's disease and amyotrophic lateral sclerosis. Although the …