Are housing circumstances associated with faster epigenetic ageing?

A Clair, E Baker, M Kumari - J Epidemiol Community Health, 2024 - jech.bmj.com
Background Numerous aspects of housing are associated with health. However, the
pathways between housing and health, particularly the psychosocial elements of housing …

[HTML][HTML] Distinct intestinal microbial signatures linked to accelerated systemic and intestinal biological aging

S Singh, LB Giron, MW Shaikh, S Shankaran… - Microbiome, 2024 - Springer
Background People living with HIV (PLWH), even when viral replication is controlled through
antiretroviral therapy (ART), experience persistent inflammation. This inflammation is partly …

Associations of epigenetic age acceleration with CVD risks across the lifespan: the Bogalusa Heart Study

X Sun, W Chen, AC Razavi, M Shi, Y Pan, C Li… - Basic to Translational …, 2024 - jacc.org
Although epigenetic age acceleration (EAA) might serve as a molecular signature of
childhood cardiovascular disease (CVD) risk factors and further promote midlife subclinical …

Dynamical network stability analysis of multiple biological ages provides a framework for understanding the aging process

G Pridham, AD Rutenberg - The Journals of Gerontology, Series …, 2024 - academic.oup.com
Widespread interest in non-destructive biomarkers of aging has led to a multitude of
biological ages that each proffers a 'true'health-adjusted individual age. While each …

[HTML][HTML] Circadian rhythm analysis using wearable-based accelerometry as a digital biomarker of aging and healthspan

J Shim, E Fleisch, F Barata - npj Digital Medicine, 2024 - nature.com
Recognizing the pivotal role of circadian rhythm in the human aging process and its
scalability through wearables, we introduce CosinorAge, a digital biomarker of aging …

Accelerated aging mediates the associations of unhealthy lifestyles with cardiovascular disease, cancer, and mortality

X Li, X Cao, J Zhang, J Fu… - Journal of the …, 2024 - Wiley Online Library
Background With two well‐validated aging measures capturing mortality and morbidity risk,
this study examined whether and to what extent aging mediates the associations of …

[HTML][HTML] Conserved epigenetic hallmarks of T cell aging during immunity and malignancy

T Mi, AG Soerens, S Alli, TG Kang, AB Vasandan… - Nature Aging, 2024 - nature.com
Chronological aging correlates with epigenetic modifications at specific loci, calibrated to
species lifespan. Such 'epigenetic clocks' appear conserved among mammals, but whether …

[HTML][HTML] Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions

E Lee, N Carreras-Gallo, L Lopez, L Turner… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Senolytics, small molecules targeting cellular senescence, have emerged as potential
therapeutics to enhance health span. However, their impact on epigenetic age remains …

Combined aerobic and strength exercise training on biological ageing in Singaporean breast cancer patients: protocol for the Breast Cancer Exercise Intervention …

PHS Sitjar, SY Tan, M Wong, J Li, RBA Jalil, H Aw… - GeroScience, 2024 - Springer
Breast cancer (BC) is the most prominent cancer amongst women, but fortunately, early
diagnosis and advances in multimodality treatments have improved patient survivability …

Clinical biomarker-based biological ageing and future risk of neurological disorders in the UK Biobank

JKL Mak, CE McMurran, S Hägg - Journal of Neurology, Neurosurgery …, 2024 - jnnp.bmj.com
Background Many common neurological disorders are associated with advancing
chronological age, but their association with biological age (BA) remains poorly understood …