Neutrophils are the most abundant innate immune cells. Multiple mechanisms allow them to
engage a wide range of metabolic pathways for biosynthesis and bioenergetics for …

Neutrophils are the most abundant, short lived, and terminally differentiated leukocytes with
distinct tiers of arsenals to counter pathogens. Neutrophils were traditionally considered …

Neutrophils are innate immune cells that constitute the first line of defense against invading
pathogens. Due to this characteristic, they are exposed to diverse immunological …

Neutrophils are a critical element of host defense and are rapidly recruited to inflammatory
sites. Such sites are frequently limited in oxygen and/or nutrient availability, presenting a …

Neutrophils utilize a variety of metabolic sources to support their crucial functions as the first
responders in innate immunity. Here, through in vivo and ex vivo isotopic tracing, we …

Neutrophils were traditionally considered as short-lived cells with abundant secretory and
protein synthetic activity. Recent studies, however, indicate neutrophils are in reality a …

Neutrophils are the most abundant leukocytes in humans and play a role in the innate
immune response by being the first cells attracted to the site of infection. While early studies …

Granulopoiesis is part of the hematopoietic hierarchic architecture, where hematopoietic
stem cells give rise to highly proliferative multipotent and lineage-committed granulocytic …

Neutrophils are recognized as an essential part of the innate immune response, but an
active debate still exists regarding the life cycle of these cells. Neutrophils first differentiate in …

Neutrophils are critical innate immune cells for the host anti-bacterial defense. Throughout
their lifecycle, neutrophils are exposed to different microenvironments and modulate their …