There is converging evidence that young blood conveys cells, vesicles, and molecules able
to revitalize function and restore organ integrity in old individuals. We assessed the effects of …

There is converging evidence that young blood conveys cells, vesicles and molecules able
to revitalize function and restore organ integrity in old individuals. Here, we assessed the …

Young blood plasma is known to confer beneficial effects on various organs in mice and
rats. However, it was not known whether plasma from young adult pigs rejuvenates old rat …

It was reported using various biological models that the administration of blood factors from
young animals to old animals could rejuvenate certain functions. To assess the anti-aging …

An experimental novel antiaging intervention strategy is based on the concept of parabiosis,
which involves long-term treatment with factors derived from young blood facilitating …

It has been known for some time that blood from young mice can positively impact aged
animals, while blood from old mice has the opposite effect. Recent studies report that …

The role of epigenetics in the modulation of longevity has not been studied in humans. To
this aim,(1) we evaluated the DNA methylation from peripheral leukocytes of 21 female …

Aging, a process associated with progressive functional decline of organs and tissues, is
inevitable. Increased physical dependence and progressive cognitive impairment are …

Background and aim Aging is one of the causes of male infertility, and abnormal global DNA
methylation and imprinting defects have been characterized in testis during biological aging …

The epigenome, which controls cell identity and function, is not maintained with 100%
fidelity in somatic animal cells. Errors in the maintenance of the epigenome lead to …