The human gut microbiome plays a significant role in health and disease. The viral
component (virome) is predominantly composed of bacteriophages (phages) and has …

ΦCrAss001, isolated from human faecal material, is the first member of the extensive
crAssphage family to be grown in pure culture. The bacteriophage infects the human gut …

Recent years have been marked by the growing interest towards virulent and temperate
bacteriophage populations inhabiting the human lower gastrointestinal tract–the gut …

CrAssphages are an extensive and ubiquitous family of tailed bacteriophages, predicted to
infect bacteria of the order Bacteroidales. Despite being found in~ 50% of individuals and …

Background Viral metagenomic studies have suggested a role for bacteriophages in
intestinal dysbiosis associated with several human diseases. However, interpretation of viral …

CrAssphages represent the most abundant virus in the human gut microbiota, but the lack of
available genome sequences for comparison has kept them enigmatic. Recently, sequence …

Intestinal phages are abundant and important components of gut microbiota, yet the isolated
and characterized representatives that infect abundant gut bacteria are sparse. Here we …

Prophages are viruses, which have integrated their genomes into the genome of a bacterial
host. The status of the prophage genome can vary from fully intact with the potential to form …

Bacteroides spp. are part of the human intestinal microbiota but can under some
circumstances become clinical pathogens. Phages are a potentially valuable therapeutic …

Crassvirales (crAss-like phages) are an abundant group of human gut-specific
bacteriophages discovered in silico. The use of crAss-like phages as human fecal indicators …