Defining benchmark outcomes for mesial temporal lobe epilepsy surgery: A global multicenter analysis of 1119 cases

R Drexler, FL Ricklefs, S Ben‐Haim, A Rada… - …, 2024 - Wiley Online Library
Objective Benchmarking has been proposed to reflect surgical quality and represents the
highest standard reference values for desirable results. We sought to determine benchmark …

[HTML][HTML] Enhancing Safety in Epilepsy Surgery (EASINESS): Study Protocol for a Retrospective, Multicenter, Open Registry

R Drexler, S Ben-Haim, CG Bien, V Borger… - Frontiers in …, 2021 - frontiersin.org
Introduction: Optimizing patient safety and quality improvement is increasingly important in
surgery. Benchmarks and clinical quality registries are being developed to assess the best …

A historical cohort of temporal lobe surgery for medically refractory epilepsy: a systematic review and meta-analysis to guide future nonrandomized controlled trial …

AT Lee, JF Burke, P Chunduru, AM Molinaro… - Journal of …, 2019 - thejns.org
OBJECTIVE Recent trials for temporal lobe epilepsy (TLE) highlight the challenges of
investigating surgical outcomes using randomized controlled trials (RCTs). Although several …

[HTML][HTML] Prognostic factors determining poor postsurgical outcomes of mesial temporal lobe epilepsy

JH Shin, EY Joo, DW Seo, YM Shon, SB Hong… - PLoS …, 2018 - journals.plos.org
Objectives To investigate the long-term postoperative outcomes and predictive factors
associated with poor surgical outcomes in mesial temporal lobe epilepsy (MTLE). Materials …

The ERSET trial of early surgery for mesial temporal lobe epilepsy: results and frustrations

RA McGovern, GM McKhann - Neurosurgery, 2012 - journals.lww.com
Pharmacoresistant epilepsy develops in approximately 25% to 30% of all epilepsy patients.
1 Mesial temporal lobe epilepsy (MTLE) patients tend to be most refractory to treatment with …

The evolution of epilepsy surgery between 1991 and 2011 in nine major epilepsy centers across the United States, Germany, and Australia

L Jehi, D Friedman, C Carlson, G Cascino, S Dewar… - …, 2015 - Wiley Online Library
Objective Epilepsy surgery is the most effective treatment for select patients with drug‐
resistant epilepsy. In this article, we aim to provide an accurate understanding of the current …

Systematic review and network meta-analysis of resective surgery for mesial temporal lobe epilepsy

P Jain, G Tomlinson, C Snead, B Sander… - Journal of Neurology …, 2018 - jnnp.bmj.com
Objective To evaluate the effectiveness of anterior temporal lobectomy (ATL) versus
selective amygdalohippocampectomy (SAH) on seizure-free outcome in patients with …

A systematic review of minimally invasive procedures for mesial temporal lobe epilepsy: too minimal, too fast?

R Wang, U Beg, V Padmanaban, TJ Abel… - …, 2021 - journals.lww.com
BACKGROUND Cortico-amygdalohippocampectomy (CAH) is effective for mesial temporal
lobe epilepsy (mTLE). Concerns regarding surgical morbidity have generated enthusiasm …

Design considerations for a multicenter randomized controlled trial of early surgery for mesial temporal lobe epilepsy

J Engel Jr, MP McDermott, S Wiebe, JT Langfitt… - …, 2010 - Wiley Online Library
Purpose: To describe the trial design for the multicenter Early Randomized Surgical
Epilepsy Trial (ERSET). Patients with pharmacoresistant epilepsy are generally referred for …

Beyond pharmacotherapy: surgical management

P Ryvlin - Epilepsia, 2003 - Wiley Online Library
Purpose: To review the recent advances in the field of temporal lobe epilepsy (TLE) surgery.
Results: TLE surgery has recently demonstrated a highly significant superiority over optimal …